CymitQuimica logo

CAS 119615-63-3

:

Olprinone hydrochloride

Description:
Olprinone hydrochloride is a pharmacological agent primarily used as a vasodilator and inotropic agent, often employed in the management of heart failure and other cardiovascular conditions. It is characterized by its ability to enhance cardiac contractility while simultaneously reducing systemic vascular resistance, which can improve cardiac output. The compound functions as a selective phosphodiesterase type 3 (PDE3) inhibitor, leading to increased levels of cyclic AMP (cAMP) in cardiac and vascular tissues. This mechanism results in both positive inotropic effects and vasodilation. Olprinone hydrochloride is typically administered intravenously due to its rapid onset of action and short half-life. In terms of physical properties, it is a white to off-white crystalline powder, soluble in water and various organic solvents. Its safety profile includes potential side effects such as hypotension and arrhythmias, necessitating careful monitoring during administration. Overall, Olprinone hydrochloride represents a valuable therapeutic option in acute and chronic heart failure management, particularly in patients who may not respond adequately to conventional treatments.
Formula:C14H10N4O·ClH
InChI:InChI=1S/C14H10N4O.ClH/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10;/h2-6,8H,1H3,(H,17,19);1H
InChI key:InChIKey=PWTBMBAQRAOAFF-UHFFFAOYSA-N
SMILES:CC1=C(C2=CN3C(C=C2)=NC=C3)C=C(C#N)C(=O)N1.Cl
Synonyms:
  • 1,2-Dihydro-5-imidazo[1,2-α]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride
  • 2-Hydroxy-5-(imidazo[1,2-a]pyridin-6-yl)-6-methylnicotinonitrile hydrochloride
  • 3-Pyridinecarbonitrile, 1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-, hydrochloride (1:1)
  • 3-Pyridinecarbonitrile, 1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-, monohydrochloride
  • 3-Pyridinecarbonitrile,1,2-Dihydro-5-(Imidazo(1,2-A)Pyridin-6-Yl)-6-Methyl-2-O
  • Coretec
  • E 1020
  • E1020
  • Imidazo[1,2-a]pyridine, 3-pyridinecarbonitrile deriv.
  • Loprinone hydrochloride
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.