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CAS 1196153-86-2

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4-Chloro-6-(trifluoromethyl)-3-pyridinamine

Description:
4-Chloro-6-(trifluoromethyl)-3-pyridinamine is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing nitrogen. The presence of a chloro group at the 4-position and a trifluoromethyl group at the 6-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and may exhibit moderate solubility in polar organic solvents. Its trifluoromethyl group enhances lipophilicity and can affect biological activity, making it of interest in pharmaceutical research. The amino group at the 3-position can participate in hydrogen bonding, influencing its interactions in biological systems. Additionally, the compound may exhibit specific reactivity patterns typical of halogenated amines, such as nucleophilic substitution or electrophilic aromatic substitution. Overall, 4-Chloro-6-(trifluoromethyl)-3-pyridinamine is notable for its potential applications in medicinal chemistry and agrochemicals, where modifications to the pyridine structure can lead to compounds with desired biological activities.
Formula:C6H4ClF3N2
InChI:InChI=1S/C6H4ClF3N2/c7-3-1-5(6(8,9)10)12-2-4(3)11/h1-2H,11H2
InChI key:InChIKey=XKRQUYRYIFNHNV-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1=CC(Cl)=C(N)C=N1
Synonyms:
  • 4-Chloro-6-(trifluoromethyl)-3-pyridinamine
  • 3-Pyridinamine, 4-chloro-6-(trifluoromethyl)-
  • 5-Amino-4-chloro-2-(trifluoromethyl)pyridine
  • 4-Chloro-6-(trifluoromethyl)
  • 4-Chloro-6-(trifluoromethyl)pyridin-3-amine, 5-Amino-4-chloro-alpha,alpha,alpha-trifluoro-2-picoline
  • 4-chloro-6-(trifluoromethyl)pyridin-3-amine
  • 4-Chloro-6-trifluoromethyl-pyridin-3-ylamine
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