CAS 119616-38-5

biotin 3-sulfo-N-hydroxysuccinimide*ester sodium

Description:

Biotin 3-sulfo-N-hydroxysuccinimide ester sodium, with the CAS number 119616-38-5, is a biotin derivative that is commonly used in biochemical applications, particularly in the field of molecular biology and bioconjugation. This compound features a sulfonate group, which enhances its solubility in aqueous solutions, making it suitable for various biological assays. The presence of the N-hydroxysuccinimide (NHS) ester moiety allows for efficient coupling to amine-containing biomolecules, facilitating the formation of stable amide bonds. Biotin, a vitamin also known as vitamin H, is a cofactor for carboxylase enzymes and plays a crucial role in fatty acid synthesis, amino acid metabolism, and gluconeogenesis. The sodium salt form of this compound ensures its stability and solubility in physiological conditions. Overall, biotin 3-sulfo-N-hydroxysuccinimide ester sodium is a valuable tool in the development of biotinylated probes, enabling the study of proteins, nucleic acids, and other biomolecules in various research and diagnostic applications.

Formula: C₁₄H₁₉N₃O₇S₂

InChI: InChI=1/C14H19N3O7S2/c18-10(17-11(19)5-9(13(17)20)26(22,23)24)4-2-1-3-8-12-7(6-25-8)15-14(21)16-12/h7-9,12H,1-6H2,(H2,15,16,21)(H,22,23,24)/t7-,8-,9?,12+/m0/s1

Synonyms:

• Sulfosuccinimidobiotin
• 1-[5-[(3aR,6S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoyl]-2,5-dioxo-pyrrolidine-3-sulfonic acid
• Biotin-NHS, Water-Soluble

Sulpho NHS biotin

CAS: 119616-38-5

Formula: C₁₄H₁₈N₃NaO₈S₂

Purity: 85%

Color and Shape: Solid

Molecular weight: 443.4278

Ref: IN-DA0081I2

Sulfo-NHS-Biotin

CAS: 119616-38-5

Sulfo-NHS-Biotin

Purity: ≥95%

Molecular weight: 443.42g/mol

Ref: 54-BUP06421

Sulfo-NHS-Biotin

CAS: 119616-38-5

Sulfo-NHS-Biotin: water-soluble for biotinylation, targets cell proteins, aids in protein detection with Streptavidin.

Formula: C₁₄H₁₈N₃NaO₈S₂

Purity: 98.69% - 99.92%

Color and Shape: Solid

Molecular weight: 443.42

Ref: TM-T19952

Sulfo-NHS-Biotin Sodium Salt

Controlled Product

CAS: 119616-38-5

Applications Sulfo-NHS-Biotin is a biotinylation reagent used for biotinylating antibody or protein that can then be used for protein detection or immobilization studies when used in conjunction with streptavidin and immobilized streptavidin. Sulfo-NHS-Biotin was shown to work most effectively when targeting cell surface proteins.
References Aekbote, B.L., et al.: Euro. Poly. J., 48, 1745 (2012); Segu, Z.M., et al.: Anal. Chem., 83, 2500 (2011); Derda, M., et al.: App. Environ. Micribiol., 75, 6827 (2009);

Formula: C₁₄H₁₈N₃O₈S₂·Na

Color and Shape: Neat

Molecular weight: 443.428

Ref: TR-S699260