CAS 119637-66-0: Metoprolol Fumarate

Description:Metoprolol fumarate is a selective beta-1 adrenergic antagonist, primarily used in the treatment of hypertension, angina pectoris, and heart failure. It is a white to off-white crystalline powder that is soluble in water and exhibits good stability under normal conditions. The substance is a salt formed from metoprolol, a beta-blocker, and fumaric acid, which enhances its solubility and bioavailability. Metoprolol fumarate works by blocking the action of certain natural substances on the heart and blood vessels, leading to a decrease in heart rate and blood pressure. Its pharmacokinetics include rapid absorption, extensive hepatic metabolism, and a relatively short half-life, necessitating careful dosing to maintain therapeutic levels. The compound is typically administered orally and is available in various formulations, including extended-release tablets, which allow for once-daily dosing. As with any medication, potential side effects may include fatigue, dizziness, and bradycardia, and it should be used with caution in patients with certain pre-existing conditions.

Formula:C₃₄H₅₄N₂O₁₀

InChI:InChI=1/2C15H25NO3.C4H4O4/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-3(6)1-2-4(7)8/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1-

Synonyms:
Metoprolol fumarate [USAN]
(+-)-1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol fumarate (2:1) (salt)
2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (+-)-, (E)-2-butanedioate (2:1) (salt)
Cgp 2175C
Lopresor OROS
Unii-Io1C09Z674
1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol (2Z)-but-2-enedioate (2:1) (salt)

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Metoprolol Fumarate REF: 45-1441287CAS: 119637-66-0	- - -	332.00 €	Fri 11 Apr 25
METOPROLOL FUMARATE (200 MG) REF: IN-DA008XK4CAS: 119637-66-0	95%	138.00 €~611.00 €	Mon 14 Apr 25
Metoprolol fumarate REF: 3D-UEA63766CAS: 119637-66-0	Min. 95%	- - -	Discontinued product