CAS 119637-71-7: 2'-O-triflyl-2,3'-anhydroxylosyluracil

Description:2'-O-triflyl-2,3'-anhydroxylosyluracil is a chemical compound that belongs to the class of modified nucleosides, specifically derivatives of uracil. This compound features a trifluoromethanesulfonyl (triflyl) group at the 2' position, which enhances its reactivity and stability in various chemical reactions. The presence of the anhydro structure indicates that it has undergone dehydration, which can influence its biological activity and interactions with nucleic acids. The modification at the 2' position can affect the compound's ability to participate in hydrogen bonding and its overall conformational properties. Such modifications are often explored in the context of nucleoside analogs for potential therapeutic applications, including antiviral and anticancer strategies. The compound's unique structure may also impact its solubility, permeability, and metabolic stability, making it a subject of interest in medicinal chemistry and drug design. As with many chemical substances, safety and handling precautions should be observed due to potential reactivity associated with the triflyl group.

Formula:C₁₀H₉F₃N₂O₇S

InChI:InChI=1/C10H9F3N2O7S/c11-10(12,13)23(18,19)22-7-6-4(3-16)20-8(7)15-2-1-5(17)14-9(15)21-6/h1-2,4,6-8,16H,3H2/t4-,6-,7+,8+/m0/s1

Synonyms:
2'-Trifluoromethane sulfonate-2,3'-anhydro-1-(beta-D-xylofuranosyl)uracil
2,3'-Anhydroxy-2'-O-triflyllosyluracil
2-Tfaou
Methanesulfonic acid, trifluoro-, 2,3-dihydro-3-(hydroxymethyl)-9-oxo-2,5-methano-5H,9H-pyrimido(2,1-b)(1,5,3)dioxazepin-11-yl ester, (2S-(2alpha,3beta,5alpha,11S*))-
(2S,3S,5R,11R)-3-(hydroxymethyl)-9-oxo-2,3-dihydro-9H-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-11-yl trifluoromethanesulfonate
2'-O-Triflyl-2,3'-anhydroxylosyluracil