CAS 1197160-78-3: Gedatolisib
Description:Gedatolisib is a small molecule inhibitor that targets the phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) pathways, which are crucial in regulating cell growth, proliferation, and survival. This dual inhibition makes Gedatolisib particularly relevant in cancer therapy, as many tumors exhibit dysregulation of these pathways. The compound is designed to enhance the efficacy of existing cancer treatments and is being investigated in clinical trials for various malignancies. Its chemical structure features specific functional groups that contribute to its activity and selectivity against the targeted kinases. Gedatolisib's pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its therapeutic potential and safety profile. As research continues, Gedatolisib may offer new avenues for treatment in oncology, particularly for patients with tumors that are resistant to conventional therapies. However, ongoing studies are necessary to fully understand its effectiveness and potential side effects in clinical settings.
Formula:C32H41N9O4
InChI:InChI=1S/C32H41N9O4/c1-38(2)27-11-13-39(14-12-27)29(42)24-5-9-26(10-6-24)34-32(43)33-25-7-3-23(4-8-25)28-35-30(40-15-19-44-20-16-40)37-31(36-28)41-17-21-45-22-18-41/h3-10,27H,11-22H2,1-2H3,(H2,33,34,43)
InChI key:InChIKey=DWZAEMINVBZMHQ-UHFFFAOYSA-N
SMILES:O=C(NC=1C=CC(=CC1)C=2N=C(N=C(N2)N3CCOCC3)N4CCOCC4)NC5=CC=C(C=C5)C(=O)N6CCC(N(C)C)CC6
- Synonyms:
- 1-(4-(4-(Dimethylamino)piperidine-1-carbonyl)phenyl)-3-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)urea
- 1-[4-[[4-(Dimethylamino)piperidin-1-yl]carbonyl]phenyl]-3-[4-[4,6-bis(morpholino)-1,3,5-triazin-2-yl]phenyl]urea
- Gedatolisib
- Pf 384
- Pf 5212384
- Pf-05212384
- Pk 1587
- Pki-587
- Urea, N-[4-[[4-(dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N′-[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]-
- N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N′-[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]urea
- See more synonyms
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Urea, N-[4-[[4-(dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]-
Ref: IN-DA000PHY
1g | To inquire | ||
1mg | 52.00 € | ||
5mg | 61.00 € | ||
10mg | 98.00 € | ||
25mg | 132.00 € | ||
100mg | 294.00 € | ||
250mg | 550.00 € |
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Gedatolisib
Ref: TM-T1970
2mg | 49.00 € | ||
5mg | 79.00 € | ||
10mg | 119.00 € | ||
25mg | 226.00 € | ||
50mg | 424.00 € | ||
100mg | 630.00 € | ||
500mg | 1,320.00 € |
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PKI 587
Ref: 3D-FP65136
10mg | 441.00 € | ||
50mg | 935.00 € |