CAS 119733-44-7: Sertraline Carbamoyl Glucuronide
Description:Sertraline Carbamoyl Glucuronide is a metabolite of sertraline, an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class. This compound is formed through the glucuronidation process, which is a phase II metabolic reaction that enhances the solubility of drugs for excretion. Characteristically, Sertraline Carbamoyl Glucuronide is a polar, water-soluble compound, which facilitates its elimination from the body. It is typically found in biological fluids, such as urine, following the administration of sertraline. The presence of this metabolite can be indicative of sertraline use and is often studied in pharmacokinetic research to understand the drug's metabolism and excretion pathways. Its chemical structure includes a carbamoyl group and a glucuronic acid moiety, contributing to its pharmacological profile. Understanding the characteristics of this metabolite is essential for evaluating the therapeutic effects and potential side effects of sertraline in clinical settings.
Formula:C24H25Cl2NO8
InChI:InChI=1/C24H25Cl2NO8/c1-27(24(33)35-23-20(30)18(28)19(29)21(34-23)22(31)32)17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(25)16(26)10-11/h2-6,8,10,12,17-21,23,28-30H,7,9H2,1H3,(H,31,32)/t12-,17-,18?,19?,20?,21?,23?/m0/s1
- Synonyms:
- (1S-cis)-1-[[4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenyl]methycarbamate]-b-D-glucopyranuronic Acid
- Sertraline Carbamoyl-O-glucuronid
- sertraline carbamoyl-O-glucuronide
- (1S-cis)-1-[[4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenyl]methycarbamate]--D-glucopyranuronic Acid
- 1-O-{[(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl](methyl)carbamoyl}hexopyranuronic acid