CAS: 1197958-12-5 - 5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine

Formula: C₂₆H₃₄ClN₆O₂P

InChI: InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4,5)34/h6-11,16-18H,12-15H2,1-5H3,(H2,28,29,30,31)

InChI key: InChIKey=OVDSPTSBIQCAIN-UHFFFAOYSA-N

SMILES: O=P(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCC(N(C)C)CC4)(C)C

Synonyms:

• 2,4-Pyrimidinediamine, 5-chloro-N²-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N⁴-[2-(dimethylphosphinyl)phenyl]-
• 5-Chloro-N²-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N⁴-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
• 5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
• Ap26113
• Brigatinib-analog
• 5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
• 2,4-Pyrimidinediamine, 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-

2,4-Pyrimidinediamine, 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-

CAS: 1197958-12-5

• Formula: C₂₆H₃₄ClN₆O₂P
• Purity: %
• Color and Shape: Solid
• Molecular weight: 529.0139

ALK-IN-1

CAS: 1197958-12-5

ALK-IN-1 (AP26113) is a potent ALK inhibitor, demonstrated ability overcome Crizotinib resistance mediated by a …

• Formula: C₂₆H₃₄ClN₆O₂P
• Purity: 100% - 97.66%
• Color and Shape: Solid
• Molecular weight: 529.01

AP 26113

CAS: 1197958-12-5

• Formula: C₂₆H₃₄ClN₆O₂P
• Color and Shape: Neat
• Molecular weight: 529.014

AP 26113

CAS: 1197958-12-5

Inhibitor of ALK kinase and EGFR receptor

• Formula: C₂₆H₃₄ClN₆O₂P
• Purity: Min. 95%
• Molecular weight: 529.01 g/mol