CAS 1197958-12-5

5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine

Description:

5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine, with CAS number 1197958-12-5, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrimidine core substituted with various functional groups. This compound features a chloro group, dimethylamino and dimethylphosphinyl moieties, and a piperidine ring, contributing to its potential biological activity. The presence of these functional groups suggests that it may exhibit properties relevant to medicinal chemistry, possibly acting as a pharmaceutical agent or a research tool in biological studies. Its molecular interactions could be influenced by the electron-donating and electron-withdrawing characteristics of the substituents, affecting solubility, stability, and reactivity. As with many compounds of this nature, understanding its characteristics requires consideration of its chemical behavior, potential applications, and safety profile in laboratory settings. Further studies would be necessary to elucidate its specific biological effects and therapeutic potential.

Formula: C₂₆H₃₄ClN₆O₂P

InChI: InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4,5)34/h6-11,16-18H,12-15H2,1-5H3,(H2,28,29,30,31)

InChI key: InChIKey=OVDSPTSBIQCAIN-UHFFFAOYSA-N

SMILES: N(C1=C(P(C)(C)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4CCC(N(C)C)CC4)=NC=C2Cl

Synonyms:

• 2,4-Pyrimidinediamine, 5-chloro-N²-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N⁴-[2-(dimethylphosphinyl)phenyl]-
• 5-Chloro-N²-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N⁴-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
• 5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
• Ap26113
• Brigatinib-analog
• 5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
• 2,4-Pyrimidinediamine, 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-

2,4-Pyrimidinediamine, 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-

CAS: 1197958-12-5

Formula: C₂₆H₃₄ClN₆O₂P

Purity: 98%

Color and Shape: Solid

Molecular weight: 529.0139

Ref: IN-DA000PNH

ALK-IN-1

CAS: 1197958-12-5

ALK-IN-1

Purity: ≥95%

Molecular weight: 529.01g/mol

Ref: 54-BUP13344

(2-((5-Chloro-2-((4-(4-(Dimethylamino)Piperidin-1-Yl)-2-Methoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)Phenyl)Dimethylphosphine Oxide

CAS: 1197958-12-5

(2-((5-Chloro-2-((4-(4-(Dimethylamino)Piperidin-1-Yl)-2-Methoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)Phenyl)Dimethylphosphine Oxide

Purity: 98%

Molecular weight: 529.01g/mol

Ref: 54-OR1029151

ALK-IN-1

CAS: 1197958-12-5

ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.

Formula: C₂₆H₃₄ClN₆O₂P

Purity: 99.74% - 99.80%

Color and Shape: Solid

Molecular weight: 529.01

Ref: TM-T3059

ALK-IN-1

CAS: 1197958-12-5

Purity: ≥98%

Molecular weight: 528.217

Ref: 10-F861662

AP 26113

Controlled Product

CAS: 1197958-12-5

Formula: C₂₆H₃₄ClN₆O₂P

Color and Shape: Neat

Molecular weight: 529.014

Ref: TR-A710005

AP 26113

CAS: 1197958-12-5

Inhibitor of ALK kinase and EGFR receptor

Formula: C₂₆H₃₄ClN₆O₂P

Purity: Min. 95%

Molecular weight: 529.01 g/mol

Ref: 3D-FD76641