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CAS 119817-90-2

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Dexloxiglumide

Description:
Dexloxiglumide is a chemical compound primarily recognized for its role as a selective antagonist of the cholecystokinin (CCK) receptor, particularly the CCK-A subtype. It is often studied for its potential therapeutic applications in gastrointestinal disorders, including its ability to modulate gastric acid secretion and influence gastrointestinal motility. Dexloxiglumide is characterized by its relatively low solubility in water, which can affect its bioavailability and pharmacokinetics. The compound is typically administered in a pharmaceutical formulation, and its efficacy is evaluated through various preclinical and clinical studies. Additionally, it has been investigated for its potential effects on appetite regulation and its implications in obesity treatment. As with many pharmacological agents, understanding its mechanism of action, side effects, and interactions with other drugs is crucial for its safe and effective use in clinical settings. Overall, Dexloxiglumide represents a significant area of research in the field of gastroenterology and pharmacology.
Formula:C21H30Cl2N2O5
InChI:InChI=1/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)/t18-/m1/s1
InChI key:InChIKey=QNQZBKQEIFTHFZ-GOSISDBHSA-N
SMILES:[C@@H](C(N(CCCCC)CCCOC)=O)(NC(=O)C1=CC(Cl)=C(Cl)C=C1)CCC(O)=O
Synonyms:
  • (4R)-4-[(3,4-Dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxopentanoic acid
  • (R)-4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid
  • (R)-4-(3,4-Dichlorobenzamido)-N-(3-methoxypropyl)-N-pentylglutaramic acid
  • <span class="text-smallcaps">D</span>-Loxiglumide
  • Dexloxiglumida
  • Dexloxiglumida [INN-Spanish]
  • Dexloxiglumide [INN]
  • Dexloxiglumidum
  • Dexloxiglumidum [INN-Latin]
  • N~2~-(3,4-dichlorobenzoyl)-N-(3-methoxypropyl)-N-pentyl-D-alpha-glutamine
  • See more synonyms
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