CAS 1198300-79-6

4-(Cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide

Description:

4-(Cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide, identified by its CAS number 1198300-79-6, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrimidine core substituted with various functional groups. This compound features a cyclopropylamino group and a piperazine moiety, indicating potential interactions with biological targets, particularly in pharmacology. The presence of an ethylsulfonyl group suggests enhanced solubility and bioavailability, which are critical for therapeutic applications. The compound's structure implies it may exhibit properties such as enzyme inhibition or receptor modulation, making it a candidate for drug development. Its specific characteristics, including melting point, solubility, and stability, would depend on the molecular interactions and the environment in which it is studied. Overall, this compound represents a class of molecules that could be explored for their potential medicinal properties, particularly in the context of treating various diseases.

Formula: C₂₀H₂₇N₇O₃S

InChI: InChI=1S/C20H27N7O3S/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(H2,22,23,24,25)

InChI key: InChIKey=BGLPECHZZQDNCD-UHFFFAOYSA-N

SMILES: N(C=1C(C(N)=O)=CN=C(NC2=CC=C(C=C2)N3CCN(S(CC)(=O)=O)CC3)N1)C4CC4

Synonyms:

• 5-Pyrimidinecarboxamide, 4-(cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-
• PRT 062070
• PRT 2017
• Cerdulatinib
• 4-(Cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide

Cerdulatinib

CAS: 1198300-79-6

Formula: C₂₀H₂₇N₇O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.5385

Ref: IN-DA008TF1

4-(Cyclopropylamino)-2-((4-(4-(Ethylsulfonyl)Piperazin-1-Yl)Phenyl)Amino)Pyrimidine-5-Carboxamide

CAS: 1198300-79-6

4-(Cyclopropylamino)-2-((4-(4-(Ethylsulfonyl)Piperazin-1-Yl)Phenyl)Amino)Pyrimidine-5-Carboxamide

Purity: 98%

Molecular weight: 445.54g/mol

Ref: 54-OR1023220

Cerdulatinib

CAS: 1198300-79-6

Cerdulatinib

Purity: ≥98%

Molecular weight: 445.54g/mol

Ref: 54-BUP12332

Cerdulatinib

CAS: 1198300-79-6

Formula: C₂₀H₂₇N₇O₃S

Color and Shape: Pale Brown Solid

Molecular weight: 445.54

Ref: 4Z-C-256001

Cerdulatinib-d8

CAS: 1198300-79-6

Formula: C₂₀H₁₉D₈N₇O₃S

Molecular weight: 453.59

Ref: 4Z-C-256002

Cerdulatinib

CAS: 1198300-79-6

Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.

Formula: C₂₀H₂₇N₇O₃S

Purity: 98.74% - 99.49%

Color and Shape: Solid

Molecular weight: 445.54

Ref: TM-T2487

Cerdulatinib

CAS: 1198300-79-6

Purity: 98%

Molecular weight: 445.19

Ref: 10-F826248

Cerdulatinib (PRT2070)

CAS: 1198300-79-6

Applications Cerdulatinib (PRT2070), acts as a novel oral and dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Preferentially selects for JAK inhibitors (JAK1 and JAK3 primarily), preventing cytokine mediated signaling and functional responses varying cell types. Potential anti-cancer agent.
References Coffey, G. et al.: J. Pharmacol. Exp. Ther., 351, 538 (2014);

Formula: C₂₀H₂₇N₇O₃S

Color and Shape: Neat

Molecular weight: 445.54

Ref: TR-C273000