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CAS 1198475-24-9

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5-bromo-6-(trifluoromethyl)-1H-indole

Description:
5-Bromo-6-(trifluoromethyl)-1H-indole is a chemical compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a bromine atom at the 5-position and a trifluoromethyl group at the 6-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and exhibits moderate solubility in organic solvents. The bromine substituent can participate in electrophilic aromatic substitution reactions, while the trifluoromethyl group enhances the compound's lipophilicity and may affect its biological activity. 5-Bromo-6-(trifluoromethyl)-1H-indole is of interest in medicinal chemistry and materials science, often investigated for its potential applications in pharmaceuticals and agrochemicals. Its unique electronic properties, stemming from the electron-withdrawing trifluoromethyl group, can also influence its interaction with biological targets, making it a subject of research in drug development. Safety and handling precautions should be observed due to the presence of halogenated compounds, which may pose environmental and health risks.
Formula:C9H5BrF3N
Synonyms:
  • 1H-Indole, 5-bromo-6-(trifluoromethyl)-
  • 5-bromo-6-(trifluoromethyl)-1H-indole
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