CAS 1199-02-6

5-Phenyl-1,3,4-oxadiazol-2(3H)-one

Description:

5-Phenyl-1,3,4-oxadiazol-2(3H)-one is a heterocyclic compound characterized by its oxadiazole ring, which consists of two nitrogen atoms and one oxygen atom integrated into a five-membered aromatic structure. This compound features a phenyl group attached to the oxadiazole, contributing to its aromatic properties and potential reactivity. It is typically a white to off-white solid and is known for its stability under standard conditions. The presence of the oxadiazole moiety often imparts interesting biological activities, making it a subject of interest in medicinal chemistry. The compound may exhibit properties such as antimicrobial, antifungal, or anti-inflammatory activities, although specific biological effects can vary based on structural modifications and the presence of substituents. Its solubility can vary depending on the solvent, and it may be used in various applications, including pharmaceuticals, agrochemicals, and materials science. As with many organic compounds, safety and handling precautions should be observed due to potential toxicity or reactivity.

Formula: C₈H₆N₂O₂

InChI: InChI=1S/C8H6N2O2/c11-8-10-9-7(12-8)6-4-2-1-3-5-6/h1-5H,(H,10,11)

InChI key: InChIKey=RFJQGIYJJLWZJP-UHFFFAOYSA-N

SMILES: O=C1OC(=NN1)C2=CC=CC=C2

Synonyms:

• 1,3,4-Oxadiazol-2(3H)-one, 5-phenyl- (9CI)
• 2-Phenyl-1,3,4-oxadiazol-5(4H)-one
• 2-Phenyl-1,3,4-oxadiazol-5-one
• 2-Phenyl-1,3,4-oxadiazolin-5-one
• 2-Phenyl-delta(sup 2)-1,3,4-oxadiazolin-5-one
• 2-Phenyl-Δ²-1,3,4-oxadiazolin-5-one
• 5-Hydroxy-2-phenyl-1,3,4-oxadiazole
• 5-Phenyl-1,3,4-Oxadiazol-2-One
• 5-Phenyl-1,3,4-oxadiazol-2-ol
• 5-Phenyl-3H-1,3,4-oxadiazol-2-one
• 5-phenyl-1,3,4-oxadiazol-2(3H)-one
• 5-phenyl-1,3,4-oxadiazol-2(5H)-one
• Nsc 525342
• Rhc 3326
• delta(sup 2)-1,3,4-Oxadiazolin-5-one, 2-phenyl-
• Δ²-1,3,4-Oxadiazolin-5-one, 2-phenyl-
• Δ2-1,3,4-Oxadiazolin-5-one, 2-phenyl-
• 2-Phenyl-Δ2-1,3,4-oxadiazolin-5-one

1,3,4-OXADIAZOL-2(3H)-ONE, 5-PHENYL-

CAS: 1199-02-6

Formula: C₈H₆N₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 162.1454

Ref: IN-DA000PUA

5-Phenyl-1,3,4-oxadiazol-2-ol

CAS: 1199-02-6

5-Phenyl-1,3,4-oxadiazol-2-ol

Purity: 95%

Molecular weight: 162.15g/mol

Ref: 54-OR910413

5-Phenyl-1,3,4-oxadiazol-2-ol

CAS: 1199-02-6

Formula: C₈H₆N₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 162.148

Ref: 10-F062914

5-Phenyl-1,3,4-oxadiazol-2-ol

CAS: 1199-02-6

5-Phenyl-1,3,4-oxadiazol-2-ol is an organic compound that belongs to the heterocyclic compounds. It is a white solid at room temperature with a melting point of 117°C. The reaction of 5-phenyl-1,3,4-oxadiazol-2-ol with hydrochloric acid gives solvents and polyelectrolytes. This compound also reacts with amines to give ring opening polymerization products and with anilines to give oxadiazolones. 5-Phenyl-1,3,4-oxadiazol-2-ol has been shown to have 5HT4 receptor agonist activity in mice and has been used as a lead compound for drug development against depression and anxiety disorders.
5HT4 receptors are located on the nerve cells in the brain and spinal cord and are involved in regulating mood and anxiety levels.

Formula: C₈H₆N₂O₂

Purity: Min. 95%

Molecular weight: 162.15 g/mol

Ref: 3D-BAA19902