CAS 1199-18-4
:6-Hydroxydopamine
Description:
6-Hydroxydopamine is a synthetic organic compound that is primarily used in neuroscience research, particularly for studying neurodegenerative diseases and the mechanisms of neuronal damage. It is a derivative of dopamine, characterized by the presence of a hydroxyl group at the 6-position of the aromatic ring. This compound is known for its neurotoxic properties, as it selectively destroys dopaminergic neurons, making it a valuable tool for creating animal models of Parkinson's disease. In terms of physical properties, 6-hydroxydopamine is typically a white to off-white solid that is soluble in water and various organic solvents. It is important to handle this compound with care due to its toxicity and potential to induce oxidative stress in biological systems. Additionally, 6-hydroxydopamine is often used in experiments involving the study of oxidative stress, apoptosis, and the role of neurotransmitters in the central nervous system. Proper safety protocols should be followed when working with this substance in laboratory settings.
Formula:C8H11NO3
InChI:InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
InChI key:InChIKey=DIVDFFZHCJEHGG-UHFFFAOYSA-N
SMILES:C(CN)C1=C(O)C=C(O)C(O)=C1
Synonyms:- 2,4,5-Trihydroxyphenethylamine
- 5-(2-Aminoethyl)-1,2,4-benzenetriol
- 6-Hydroxydopamine
- Dopamine, 6-hydroxy-
- Oxidopamin
- Oxidopamina
- Oxidopamine
- Topamine
- 1,2,4-Benzenetriol, 5-(2-aminoethyl)-
- 5-(2-aminoethyl)benzene-1,2,4-triol
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