CAS 119904-90-4

(S)-3-Aminoquinuclidine dihydrochloride

Description:

(S)-3-Aminoquinuclidine dihydrochloride is a chemical compound characterized by its chiral quinuclidine structure, which is a bicyclic amine. This substance is typically encountered as a dihydrochloride salt, enhancing its solubility in aqueous solutions. The compound features an amino group that contributes to its basicity and potential reactivity in various chemical reactions. It is often studied for its pharmacological properties, particularly in the context of neuroscience, as it may interact with neurotransmitter systems. The presence of the dihydrochloride form indicates that it can exist as a stable, crystalline solid, which is advantageous for handling and storage. Additionally, the stereochemistry of the (S)-enantiomer suggests specific biological activity, as chirality can significantly influence the interaction of the molecule with biological targets. Overall, (S)-3-Aminoquinuclidine dihydrochloride is of interest in both synthetic chemistry and medicinal applications, warranting further investigation into its properties and potential uses.

Formula: C₇H₁₆Cl₂N₂

InChI: InChI=1/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17+/m1/s1

InChI key: InChIKey=STZHBULOYDCZET-XCUBXKJBSA-N

SMILES: N[C@H]1C2CCN(C1)CC2.Cl

Synonyms:

• (3R)-3-ammonio-1-azoniabicyclo[2.2.2]octane dichloride
• (3S)-1-Azabicyclo[2.2.2]octan-3-amine dihydrochloride
• (3S)-3-Aminoquinuclidine dihydrochloride
• (3aR)-2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
• (3aS)-2-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
• (S)-(-)-3-Amino Quinuclidine Dihcl
• (S)-Quinuclidin-3-amine dihydrochloride
• 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (3S)-
• 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (S)-
• 1-Azabicyclo[2.2.2]octan-3-amine, hydrochloride (1:2), (3S)-
• 3(S)-Aminoquinuclidine dihydrochloride
• S-(-)-3-Aminoquinuclidine 2HCl
• S-3-Aminoquinuclidine dihydrochloride
• (S)-3-Aminoquinuclidine dihydrochloride
• (S)-3-Aminoquinuclidine DiHCl
• (3as)-2-(3s)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one monohydrochloride
• (S)-(-)-3-Aminoquinuclidine dihydrochloride ,98% [ee>99%]
• (S)-3-AMINOQUINUCLIDINE HYDROCHLORIDE
• (3S)-Quinuclidin-3-amine dihydrochloride 97%
• (S)-3-AMINOQUINUCLIDINE DIHYDROCHLORIDE 98%
• S-(-)-3-Aminoquinuclidine dihydrocloride
• (3S)-QUINUCLIDIN-3-AMINE DIHYDROCHLORIDE
• PALONOSETRON HCL
• 1-azabicyclo[2,2,2]octan-3-amine,dihydrochloride,(S)
• (S)-(-)-3-AMINOQUINUCLIDINE
• INTERMEDIATE OF PALONOSETRON HCL
• (S)-1-Azabicyclo[2.2.2]octan-3-amine dihydrochloride

(S)-(-)-3-Aminoquinuclidine Dihydrochloride

CAS: 119904-90-4

Formula: C₇H₁₄N₂·2HCl

Purity: >98.0%(T)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 199.12

Ref: 3B-A2434

(S)-3-Aminoquinuclidine DiHCl

CAS: 119904-90-4

Formula: C₇H₁₆Cl₂N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 199.1213

Ref: IN-DA00327P

Palonosetron hydrochloride

CAS: 119904-90-4

Formula: C₁₉H₂₅ClN₂O

Molecular weight: 332.87

Ref: 7W-GP9972

(3S)-1-Azabicyclo[2.2.2]octan-3-amine Dihydrochloride ((3S)-3-Aminoquinuclidine Dihydrochloride)

CAS: 119904-90-4

Color and Shape: Neat

Ref: 86-MM3779.09

(3S)-3-Aminoquinuclidine dihydrochloride

CAS: 119904-90-4

(3S)-3-Aminoquinuclidine dihydrochloride

Formula: C₇H₁₄N₂·2ClH

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 199.12g/mol

Ref: 54-OR6149

(S)-(-)-3-Aminoquinuclidine 2HCl

CAS: 119904-90-4

(S)-(-)-3-Aminoquinuclidine 2HCl is a cholinergic agonist that has been shown to be effective in inducing the release of acetylcholine from brain synaptosomes. This drug binds to the nicotinic acetylcholine receptor (nAChR) and inhibits the action of the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the synaptic cleft. The drug is also able to cross the blood-brain barrier and bind to receptors on neurons. It has been shown that this drug can be used as an imaging agent for molecular magnetic resonance tomography (MRT), with high sensitivity and specificity.

Formula: C₇H₁₆Cl₂N₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 199.12 g/mol

Ref: 3D-FA03745

(S)-3-Aminoquinuclidine dihydrochloride

CAS: 119904-90-4

Formula: C₇H₁₆Cl₂N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 199.12

Ref: 10-F093049

(3S)-Aminoquinuclidine Dihydrochloride

Controlled Product

CAS: 119904-90-4

Applications Palonosetron intermediate.
References Cappelli, A., et al.: Bioorg. Med. Chem., 10, 779 (2002), Dressen, D., et al.: J. Med. Chem., 50, 5161 (2007),

Formula: C₇H₁₄N₂·2ClH

Color and Shape: Neat

Molecular weight: 199.121

Ref: TR-A629190