CAS 119945-59-4

3-Ethyl 5-methyl (4R)-4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Description:

3-Ethyl 5-methyl (4R)-4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, with CAS number 119945-59-4, is a chemical compound characterized by its complex structure, which includes a pyridine ring substituted with various functional groups. This compound features two carboxylate ester groups, contributing to its potential reactivity and solubility properties. The presence of the 2,3-dichlorophenyl moiety indicates that it may exhibit significant biological activity, possibly influencing its pharmacological properties. The stereochemistry denoted by (4R) suggests that the compound has specific spatial arrangements that could affect its interactions with biological targets. Additionally, the ethyl and methyl substituents on the pyridine ring may enhance lipophilicity, influencing its absorption and distribution in biological systems. Overall, this compound's unique structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals or agrochemicals, although specific biological activities would require further investigation.

Formula: C₁₈H₁₉Cl₂NO₄

InChI: InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3/t15-/m1/s1

InChI key: InChIKey=RZTAMFZIAATZDJ-OAHLLOKOSA-N

SMILES: C(OCC)(=O)C=1[C@@H](C(C(OC)=O)=C(C)NC1C)C2=C(Cl)C(Cl)=CC=C2

Synonyms:

• (+)-Felodipine
• (4R)-4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
• 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester, (4R)-
• 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester, (4R)-
• 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester, (R)-
• 3-Ethyl 5-methyl (4R)-4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
• (R)-Felodipine

3-ethyl 5-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS: 119945-59-4

Formula: C₁₈H₁₉Cl₂NO₄

Color and Shape: Solid

Molecular weight: 384.2538

Ref: IN-DA000PW8

(R)-(+)-Felodipine

Controlled Product

CAS: 119945-59-4

Applications A dihydropyridine calcium channel blocker. Enantiomer R of Felodipine.
References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981), Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002), O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006),

Formula: C₁₈H₁₉Cl₂NO₄

Color and Shape: Neat

Molecular weight: 384.25

Ref: TR-F232365

(R)-(+)-Felodipine

CAS: 119945-59-4

Voltage-gated calcium channel blocker

Formula: C₁₈H₁₉Cl₂NO₄

Purity: Min. 95%

Molecular weight: 384.25 g/mol

Ref: 3D-FF23236