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CAS 1200-22-2

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α-Lipoic acid

Description:
α-Lipoic acid, also known as thioctic acid, is a naturally occurring compound that plays a crucial role in mitochondrial bioenergetics as a cofactor for several enzyme complexes involved in energy metabolism. It is a potent antioxidant, capable of scavenging free radicals and regenerating other antioxidants, such as vitamins C and E. The chemical structure of α-lipoic acid features a dithiolane ring, which contributes to its redox properties. It is soluble in both water and lipids, allowing it to exert effects in various biological environments. α-Lipoic acid is often studied for its potential therapeutic applications, including its role in managing diabetes, neurodegenerative diseases, and metabolic disorders. Additionally, it has been investigated for its ability to improve insulin sensitivity and reduce oxidative stress. Due to its diverse biological functions, α-lipoic acid is available as a dietary supplement, although its efficacy and safety in various health conditions continue to be the subject of ongoing research.
Formula:C8H14O2S2
InChI:InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key:InChIKey=AGBQKNBQESQNJD-SSDOTTSWSA-N
SMILES:C(CCCC(O)=O)[C@@H]1CCSS1
Synonyms:
  • (3R)-1,2-Dithiolane-3-pentanoic acid
  • (R)-(+)-1,2-Dithiolane-3-pentanoic acid
  • (R)-(+)-|á-Lipoic Acid
  • (R)-5-(1,2-Dithiolan-3-yl)pentanoicacid
  • (R)-Lipoic acid
  • 1,2-Dithiolane-3-pentanoic acid, (3R)-
  • 1,2-Dithiolane-3-pentanoic acid, (R)-
  • 1,2-Dithiolane-3-valeric acid, (+)-
  • Arlipoic acid
  • Berlition
  • See more synonyms
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Found 11 products.
  • 1,2-Dithiolane-3-pentanoic acid, (3R)-

    CAS:
    Formula:C8H14O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:206.3256

    Ref: IN-DA000Q29

    1g
    26.00€
    5g
    30.00€
    10g
    37.00€
    25g
    52.00€
    100g
    112.00€
    250g
    219.00€
    500g
    319.00€
  • (R)-(+)-α-Lipoic acid

    CAS:
    Formula:C8H14O2S2
    Purity:≥ 98.0%
    Color and Shape:Faint yellow to yellow powder or crystals
    Molecular weight:206.33

    Ref: 7W-GK0418

    5g
    45.00€
    10g
    74.00€
    25g
    145.00€
    10kg
    21,127.00€
  • Lipoic acid

    CAS:
    <p>Lipoic acid</p>
    Purity:≥95%
    Molecular weight:206.33g/mol

    Ref: 54-BUP18248

    5g
    90.00€
    10g
    121.00€
    500mg
    51.00€
  • (R)-5-(1,2-Dithiolan-3-Yl)Pentanoic Acid

    CAS:
    (R)-5-(1,2-Dithiolan-3-Yl)Pentanoic Acid
    Purity:98%
    Molecular weight:206.33g/mol

    Ref: 54-OR1008529

    5g
    30.00€
    25g
    48.00€
    100g
    152.00€
    500g
    626.00€
    2.5kg
    2,688.00€
  • (R)-α-Lipoic Acid

    CAS:
    Formula:C8H14O2S2
    Purity:>98.0%(T)(HPLC)
    Color and Shape:Light orange to Yellow to Green powder to crystaline
    Molecular weight:206.32

    Ref: 3B-L0207

    5g
    77.00€
    25g
    229.00€
    100g
    648.00€
  • (R)-Thioctic Acid

    CAS:
    Formula:C8H14O2S2
    Molecular weight:206.32

    Ref: 4Z-T-8814

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Lipoic acid

    CAS:
    <p>Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid.</p>
    Formula:C8H14O2S2
    Purity:99.79%
    Color and Shape:Yellow Crystalline Solid
    Molecular weight:206.33
  • (R)-(+)-a-Lipoic Acid

    CAS:
    <p>Applications A fat-metabolism stimulator. Antioxidant.<br>References Plotzker, R., et al.: Am. J. Med. Sci., 283, 79 (1982), Evans, J., et al.: Diabetes Technol. Ther., 2, 401 (2000), Konrad, D., et al.: Diabetes, 50, 1464 (2001), Lockhart, B., et al.: Brain Res., 855, 292 (2000),<br></p>
    Formula:C8H14O2S2
    Color and Shape:Light Yellow
    Molecular weight:206.33

    Ref: TR-L468725

    5g
    170.00€
    50mg
    105.00€
    500mg
    145.00€
  • (R)-(+)-a-Lipoic acid

    CAS:
    <p>(R)-(+)-a-Lipoic acid is a naturally occurring compound with antioxidant properties in the body. It is found in high concentrations in the kidney, liver, and pancreas, and is an important cofactor for mitochondrial enzymes that catalyze the oxidation of pyruvate to acetyl CoA. (R)-(+)-a-Lipoic acid has been shown to be effective against cisplatin-induced nephrotoxicity, oxidative injury caused by ischemia–reperfusion injury, diabetic neuropathy and other conditions. The exact mechanism of action of (R)-(+)-a-Lipoic acid is not known but it may be due to its ability to restore mitochondrial membrane potential or inhibit reactive oxygen species production. (R)-(+)-a-Lipoic acid has also been shown to reduce body mass index and glomerular filtration rate in mice.</p>
    Formula:C8H14O2S2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:206.33 g/mol

    Ref: 3D-FL24904

    25g
    203.00€
    50g
    353.00€
    100g
    594.00€
    250g
    949.00€
    500g
    1,193.00€
  • (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid

    CAS:
    Formula:C8H14O2S2
    Purity:98%
    Color and Shape:Solid, Slightly pale yellow - Yellow powder
    Molecular weight:206.32

    Ref: 10-F091927

    1g
    13.00€
    5g
    16.00€
    10g
    23.00€
    25g
    46.00€
    100g
    98.00€
    500g
    397.00€
  • R-Thiotic Acid

    CAS:
    Formula:C8H14O2S2
    Molecular weight:206.32

    Ref: ST-EA-CP-T110069

    10mg
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    25mg
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    50mg
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    100mg
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