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CAS 120012-04-6

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Dihydro Donepezil

Description:
Dihydro Donepezil, identified by its CAS number 120012-04-6, is a chemical compound that serves as a derivative of Donepezil, a well-known acetylcholinesterase inhibitor used primarily in the treatment of Alzheimer's disease. This compound features a bicyclic structure that contributes to its pharmacological properties. Dihydro Donepezil is characterized by its ability to enhance cholinergic neurotransmission by inhibiting the breakdown of acetylcholine, thereby improving cognitive function in patients with neurodegenerative disorders. The compound exhibits moderate lipophilicity, which aids in its ability to cross the blood-brain barrier, a critical factor for central nervous system activity. Additionally, Dihydro Donepezil has been studied for its potential neuroprotective effects and may possess a favorable safety profile compared to its parent compound. Its synthesis and characterization involve various organic chemistry techniques, and ongoing research continues to explore its efficacy and mechanism of action in neurological contexts.
Formula:C24H31NO3
InChI:InChI=1/C24H31NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20,24,26H,8-13,16H2,1-2H3
SMILES:COc1cc2CC(CC3CCN(CC3)Cc3ccccc3)C(c2cc1OC)O
Synonyms:
  • 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-ol
  • Donepezil-007
  • Donepezil Dihydro IMpurity
  • 2,3-Dihydro-5,6-diMethoxy-2-[[1-(phenylMethyl)-4-piperidinyl]Methyl]-1H-inden-1-ol
  • Dihydro Donepezil
  • Donepezil IMpurity-VI
  • Donepezil Impurity 18 (Mixture of Diastereomers)
  • (Mixture of Diastereomers)
  • 1H-Inden-1-ol, 2,3-dihydro-5,6- diMethoxy-2-[[1-(phenylMethyl)-4-piperidinyl]Methyl]-
  • Donepezil impurity 13/Dihydro Donepezil Impurity/2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-ol
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