CAS 1200126-26-6

GNE-900

CAS: 1200126-26-6

GNE-900

Purity: ≥95%

Molecular weight: 367.45g/mol

Ref: 54-BUP00918

GNE-900

CAS: 1200126-26-6

GNE-900 is a potent inhibitor of the tyrosine kinase Bcr-Abl and has been shown to induce apoptotic cell death in human leukemia cells. GNE-900 inhibits the activity of chk1, which is a major checkpoint for cell cycle progression. The compound also has potentiating effects on radiation and chemotherapeutic agents. GNE-900 is currently undergoing clinical trials for various cancers, including chronic myelogenous leukemia (CML), acute lymphoblastic leukemia (ALL), and non-Hodgkin's lymphoma.

Formula: C₂₃H₂₁N₅

Purity: Min. 95%

Molecular weight: 367.4 g/mol

Ref: 3D-AYB12626

GNE-900

CAS: 1200126-26-6

GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 µM, respectively

Formula: C₂₃H₂₁N₅

Purity: 99.20%

Color and Shape: Solid

Molecular weight: 367.45

Ref: TM-T71259