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CAS 120013-56-1

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6-O-DESMETHYL DONEPEZIL

Description:
6-O-Demethyl Donepezil, with the CAS number 120013-56-1, is a chemical compound related to Donepezil, which is primarily used in the treatment of Alzheimer's disease. This substance is characterized by its structural modification, specifically the removal of a methoxy group at the 6-position of the Donepezil molecule. As a result, it may exhibit different pharmacological properties compared to its parent compound. Typically, compounds like 6-O-Demethyl Donepezil are studied for their potential effects on acetylcholinesterase inhibition, which is crucial for enhancing cholinergic neurotransmission in the brain. The compound may also possess varying degrees of lipophilicity, solubility, and bioavailability, influencing its therapeutic efficacy and safety profile. Research into such derivatives often focuses on their potential benefits in cognitive enhancement and neuroprotection, as well as their side effects. Overall, 6-O-Demethyl Donepezil represents a significant area of interest in medicinal chemistry, particularly in the context of neurodegenerative diseases.
Formula:C23H27NO3
Synonyms:
  • 1-Benzyl-4-[(6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methylpiperidine
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