CAS 120014-06-4: Donepezil

Description: Donepezil is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and other cognitive disorders. Its chemical formula is C24H29NO3, and it features a piperidine ring, which is crucial for its pharmacological activity. Donepezil enhances cholinergic function by increasing the levels of acetylcholine in the brain, thereby improving cognitive function and memory in patients with Alzheimer's. The substance is typically administered orally and is known for its relatively good bioavailability and moderate half-life, allowing for once-daily dosing. Donepezil is generally well-tolerated, though it may cause side effects such as nausea, diarrhea, insomnia, and muscle cramps. Its mechanism of action and therapeutic effects make it a significant compound in the management of neurodegenerative diseases, contributing to the symptomatic relief of cognitive decline. As with any medication, it is essential for patients to consult healthcare professionals for appropriate use and monitoring.

Formula: C₂₄H₂₉NO₃

InChI: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3

InChI key: InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N

SMILES: O=C1C2=CC(OC)=C(OC)C=C2CC1CC3CCN(CC=4C=CC=CC4)CC3

Synonyms:

• (±)-E 2020
• 1-Benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl]methylpiperidine
• 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
• 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
• 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one
• 2-(1-Benzyl-piperidin-4-ylmethyl)-5,6-dimethoxy-indan-1-one
• 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
• 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
• 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
• Donepesil
• Donepezil base
• Neuripezil
• Tonizep

Donepezil Hydrochloride

CAS: 120011-70-3 120014-06-4

• Formula: C₂₄H₂₉NO₃·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 415.96

1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-

CAS: 120014-06-4

• Formula: C₂₄H₂₉NO₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 379.4920

Donepezil

CAS: 120014-06-4

• Formula: C₂₄H₂₉NO₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 379.50

Donepezil-d4 HCl

CAS: 120014-06-4

• Formula: C₂₄H₂₅NO₃D₄·HCl
• Molecular weight: 383.53 36.46

Donepezil

CAS: 120014-06-4

Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE).

• Formula: C₂₄H₂₉NO₃
• Purity: 99.8%
• Color and Shape: White Or Almost White Crystal Powder
• Molecular weight: 379.49

Donepezil

CAS: 120014-06-4

Applications Donepezil is a cholinesterase inhibitors. References Gawel, K., et al.: J. Psychopharmacol., 30, 676 …

• Formula: C₂₄H₂₉NO₃
• Color and Shape: White
• Molecular weight: 379.49

2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

CAS: 120014-06-4

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 379.5

2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

CAS: 120014-06-4

Please enquire for more information about 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one including the price, delivery time and more detailed …

• Formula: C₂₄H₂₉NO₃
• Purity: Min. 95%
• Molecular weight: 379.5 g/mol