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CAS 120041-08-9

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1,4,7,10-Tetraazacyclododecane-1,4,7-triaceticacid, 10-(2-hydroxypropyl)-

Description:
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-(2-hydroxypropyl)-, commonly referred to as a derivative of cyclen, is a polyamine compound characterized by its cyclic structure containing four nitrogen atoms and multiple carboxylic acid functional groups. This compound features a tetraazacyclododecane backbone, which provides a stable chelating environment for metal ions, making it useful in coordination chemistry and potential applications in medical imaging and drug delivery. The presence of triacetic acid groups enhances its ability to form stable complexes with various metal ions, while the hydroxypropyl substituent contributes to its solubility and reactivity. The compound is typically synthesized through multi-step organic reactions, and its properties can be influenced by pH and the presence of other ligands. Its applications extend to areas such as radiopharmaceuticals, where it can be used to improve the targeting and efficacy of therapeutic agents. Overall, this compound exemplifies the intersection of organic chemistry and medicinal applications, showcasing the importance of ligand design in coordination chemistry.
Formula:C17H32N4O7
Synonyms:
  • 10-(2-Hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triaceticacid
  • Hp-Do3A
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