CAS 120200-06-8

6,6,6-Trifluoro-D-norleucine

Description:

6,6,6-Trifluoro-D-norleucine is a synthetic amino acid derivative characterized by the presence of three fluorine atoms attached to the sixth carbon of the norleucine backbone. This modification significantly alters its chemical properties, enhancing its hydrophobicity and potentially influencing its interactions in biological systems. The trifluoromethyl group can also impart unique electronic characteristics, making it of interest in medicinal chemistry and drug design. As a non-canonical amino acid, it may be utilized in the study of protein folding, stability, and function, as well as in the development of peptide-based therapeutics. The compound is typically stable under standard laboratory conditions but may require specific handling due to the presence of fluorine, which can affect reactivity and solubility. Its applications may extend to various fields, including biochemistry, pharmacology, and materials science, where fluorinated compounds are often explored for their distinctive properties.

Formula: C₆H₁₀F₃NO₂

InChI: InChI=1S/C6H10F3NO2/c7-6(8,9)3-1-2-4(10)5(11)12/h4H,1-3,10H2,(H,11,12)/t4-/m1/s1

InChI key: InChIKey=RUEWGWBXZIDRJY-SCSAIBSYSA-N

SMILES: C(C[C@H](C(O)=O)N)CC(F)(F)F

Synonyms:

• (R)-2-Amino-6,6,6-trifluorohexanoic acid
• (2R)-2-Amino-6,6,6-trifluorohexanoic acid
• D-Norleucine, 6,6,6-trifluoro-
• 6,6,6-Trifluoro-D-norleucine
• (D)-2-Amino-6,6,6-trifluorohexanoic acid