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CAS 1202003-44-8

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H-α-Me-Lys(Boc)-OH

Description:
H-α-Me-Lys(Boc)-OH, also known as Nα-Boc-α-methyl-Lysine, is a protected form of the amino acid lysine, which is characterized by the presence of a tert-butyloxycarbonyl (Boc) group that serves as a protective group for the amino functionality. This compound features an α-methyl group, which differentiates it from standard lysine, potentially influencing its steric and electronic properties. The Boc group is commonly used in peptide synthesis to protect the amine from unwanted reactions during the coupling process. H-α-Me-Lys(Boc)-OH is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its structure allows for the introduction of lysine into peptides while maintaining the integrity of the amino group until deprotection is desired. This compound is valuable in the field of peptide chemistry and drug development, particularly in the synthesis of modified peptides with enhanced properties.
Formula:C12H24N2O4
Synonyms:
  • H-alpha-Me-Lys(Boc)-OH
  • Alpha-Me-Lys(Boc)-OH
  • (2S)-2-amino-6-{[(tert-butoxy)carbonyl]amino}-2-methylhexanoic acid
  • L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-2-methyl-
  • H-α-Me-Lys(Boc)-OH
  • H-α-Me-L-Lys(Boc)-OH
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