CAS 120202-71-3: (R)-Clopidogrel bisulfate

Description: (R)-Clopidogrel bisulfate is an antiplatelet medication primarily used to prevent blood clots in patients with cardiovascular diseases. It is a prodrug that requires metabolic activation to exert its therapeutic effects, specifically inhibiting the P2Y12 receptor on platelets, thereby preventing platelet aggregation. The compound is characterized by its chiral nature, with the (R)-enantiomer being the active form responsible for its pharmacological activity. Clopidogrel bisulfate is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability is affected by first-pass metabolism. The substance is often formulated as a bisulfate salt to enhance its solubility and stability. Common side effects include bleeding complications, gastrointestinal disturbances, and, in rare cases, hypersensitivity reactions. Due to its mechanism of action, it is crucial for patients to be monitored for signs of bleeding, especially when used in conjunction with other anticoagulants or antiplatelet agents. Overall, (R)-Clopidogrel bisulfate plays a significant role in the management of thrombotic disorders.

Formula: C₁₆H₁₆ClNO₂S·H₂O₄S

InChI: InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m1./s1

InChI key: InChIKey=FDEODCTUSIWGLK-XFULWGLBSA-N

SMILES: O=C(OC)C(C=1C=CC=CC1Cl)N2CC=3C=CSC3CC2.O=S(=O)(O)O

Synonyms:

• (R)-(-)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
• (R)-(-)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
• (R)-Clopidogrel bisulfate
• (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
• Clopidogrel Related Compound C
• Methyl(-)-(R)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, hydrogen sulfate
• Sr 25989C
• Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αR)-, sulfate (1:1)
• methyl (2R)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate

Clopidogrel Related Compound C (methyl (-)-(R)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, hydrogen sulfate)

CAS: 120202-71-3

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₆H₁₆ClNO₂S·H₂SO₄
• Color and Shape: White Powder
• Molecular weight: 321.05903

(R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate

CAS: 120202-71-3

• Formula: C₁₆H₁₈ClNO₆S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 419.9002

Clopidogrel EP Impurity C Sulfate (Clopidogrel USP Related Compound C, (R)-Clopidogrel Sulfate)

CAS: 120202-71-3

• Formula: C₁₆H₁₆ClNO₂S·H₂SO₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 321.82 98.07

Methyl (2R)-(2-Chlorophenyl)[6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]acetate Hydrogen Sulfate ((R)-Clopidogrel Hydrogen Sulfate)

CAS: 120202-71-3

• Formula: C₁₆H₁₆ClNO₂S·H₂O₄S
• Color and Shape: Neat
• Molecular weight: 419.90

Clopidogrel Related Compound C

CAS: 120202-71-3

Clopidogrel Related Compound C is a useful organic compound for research related to life sciences.

• Formula: C₁₆H₁₈ClNO₆S₂
• Color and Shape: Liquid
• Molecular weight: 419.89

R-(-)-Clopidogrel Hydrogen Sulfate

CAS: 120202-71-3

Impurity Clopidogrel EP Impurity C Stability Very Hygroscopic Applications R-(-)-Clopidogrel Hydrogen Sulfate (Clopidogrel EP Impurity …

• Formula: C₁₆H₁₆ClNO₂S·H₂O₄S
• Color and Shape: White
• Molecular weight: 419.90

R-(-)-Clopidogrel hydrogen sulfate

CAS: 120202-71-3

R-(-)-Clopidogrel hydrogen sulfate is a prodrug of clopidogrel, which is an antiplatelet agent. It is …

• Formula: C₁₆H₁₈ClNO₆S₂
• Purity: Min. 98 Area-%
• Color and Shape: White Slightly Yellow Powder
• Molecular weight: 419.02641