CAS 120210-48-2

Tenidap

Description:

Tenidap is a chemical compound that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily recognized for its potential anti-inflammatory and analgesic properties, making it relevant in the treatment of conditions such as arthritis. The compound functions by inhibiting specific enzymes involved in the inflammatory process, thereby reducing pain and swelling. Tenidap is characterized by its unique molecular structure, which includes functional groups that contribute to its biological activity. It is typically administered in oral form and has been studied for its pharmacokinetics, including absorption, distribution, metabolism, and excretion. While it has shown promise in clinical settings, the use of Tenidap may be associated with side effects common to NSAIDs, such as gastrointestinal discomfort or cardiovascular risks. As with any pharmaceutical agent, its therapeutic use should be guided by a healthcare professional, considering the patient's specific health profile and potential drug interactions.

Formula: C₁₄H₉ClN₂O₃S

InChI: InChI=1/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20)

InChI key: InChIKey=LXIKEPCNDFVJKC-QXMHVHEDSA-N

SMILES: C(\O)(=C\1/C=2C(N(C(N)=O)C1=O)=CC=C(Cl)C2)/C3=CC=CS3

Synonyms:

• (3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide
• (Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamide
• 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
• 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (Z)-
• 5-chloro-2-hydroxy-3-(thiophen-2-ylcarbonyl)-1H-indole-1-carboxamide
• 5-chloro-2-oxo-3-(thiophen-2-ylcarbonyl)-2,3-dihydro-1H-indole-1-carboxamide
• Cp 66,248
• Tenidap [USAN:INN:BAN]
• Tenidapum
• Tenidapum [INN-Latin]
• Unii-9K7Cj74Onh
• Tenidap
• 5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide
• AKOS 91367
• CP66248,CP-66248-2
• indole-1-carboxaMide
• (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-

Tenidap

CAS: 120210-48-2

Formula: C₁₄H₉ClN₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 320.7509

Ref: IN-DA008T8Z

Tenidap

CAS: 120210-48-2

Tenidap

Purity: ≥98%

Molecular weight: 320.75g/mol

Ref: 54-BUP12823

Tenidap

CAS: 120210-48-2

Formula: C₁₄H₉ClN₂O₃S

Molecular weight: 320.75

Ref: 7W-GP5088

Tenidap

CAS: 120210-48-2

Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.

Formula: C₁₄H₉ClN₂O₃S

Purity: 98.56% - 99.42%

Color and Shape: Solid

Molecular weight: 320.75

Ref: TM-T17036

Tenidap

Controlled Product

CAS: 120210-48-2

Applications Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.
References Moilanen, et al.: Eicosanoids, 1, 35 (1988), Kirchner, et al.: J. Pharmacol. Exp. Ther., 282, 1094 (1997), Liu, et al.: Eur. J. Pharmacol., 435, 153 (2002),

Formula: C₁₄H₉ClN₂O₃S

Color and Shape: Neat

Molecular weight: 320.75

Ref: TR-T018330

Tenidap

CAS: 120210-48-2

Tenidap is a synthetic anti-inflammatory drug, which is derived from the chemical modification of nonsteroidal anti-inflammatory drugs (NSAIDs). It functions as both a cyclooxygenase (COX) inhibitor and a modulator of cytokine production. This dual mode of action allows Tenidap to simultaneously reduce the synthesis of prostaglandins by inhibiting COX enzymes and suppress the production of pro-inflammatory cytokines like interleukin-1 and tumor necrosis factor. This makes it unique compared to traditional NSAIDs.

Formula: C₁₄H₉ClN₂O₃S

Purity: Min. 95%

Molecular weight: 320.75 g/mol

Ref: 3D-VEA21048