CAS 1202402-40-1

(S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyriMidin-5-ylaMine

Description:

The chemical substance known as (S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamine, with the CAS number 1202402-40-1, is a complex organic compound characterized by its multi-ring structure and various functional groups. This compound features a triazolo-pyrimidine core, which is known for its potential biological activity, particularly in medicinal chemistry. The presence of a furan ring and a tetrahydrofuran moiety suggests that it may exhibit interesting interactions with biological targets, potentially influencing its pharmacological properties. The stereochemistry indicated by the (S) configuration may also play a crucial role in its biological activity, as chirality can significantly affect the behavior of molecules in biological systems. Overall, this compound's unique structural features may contribute to its potential applications in drug development or as a research tool in various fields of chemistry and biology.

Formula: C₂₀H₂₁N₇O₃

Synonyms:

• Triazolo-pyramidine derivative
• V81444
• CPI-444
• CPI-444;CPI 444;CPI444
• 7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine
• 3H-1,2,3-Triazolo[4,5-d]pyrimidin-5-amine, 7-(5-methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-
• Ciforadenant
• (S)-5-Amino-7-(5-methyl-2-furyl)-3-[[6-[[(3-tetrahydrofuranyl)oxy]methyl]-2-pyridyl]methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidine
• (S)-3-{6-[(tetrahydrofuran-3-yloxy)methyl]pyridin-2-ylmethyl}-7-(5-methyl-2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamine
• (S)-7-(5-Methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
• CPI-444 AND7648
• CPD1110
• (S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyriMidin-5-ylaMine
• CPI-444 (V81444)
• CS-2828

7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine

CAS: 1202402-40-1

Formula: C₂₀H₂₁N₇O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 407.4258

Ref: IN-DA003AHO

Ciforadenant

CAS: 1202402-40-1

Ciforadenant

Purity: 98%

Molecular weight: 407.43g/mol

Ref: 54-OR1022914

CPI-444

CAS: 1202402-40-1

CPI-444

Purity: ≥98%

Molecular weight: 407.43g/mol

Ref: 54-BUP12284

CPI-444

CAS: 1202402-40-1

CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.

Formula: C₂₀H₂₁N₇O₃

Purity: 98.78%

Color and Shape: Solid

Molecular weight: 407.43

Ref: TM-T7183

CPI 444

CAS: 1202402-40-1

CPI 444 is a monoclonal antibody that binds to the adenosine receptor. It has been shown to inhibit the growth of tumor cells in mice, with an IC50 of 1.3 mg/kg. CPI 444 has also been shown to inhibit the proliferation of tumor cells in vitro by blocking cell cycle progression through G1 phase and arresting cells in G2 phase. This drug is being investigated as a potential treatment for cancer, including urothelial carcinoma and renal cell cancer, as well as other solid tumours. The mechanism of action of CPI 444 is not clear but may be due to its ability to induce death protein-mediated apoptosis or alter the microenvironment by binding to toll-like receptors on immune cells.

Formula: C₂₀H₂₁N₇O₃

Purity: Min. 95%

Molecular weight: 407.43 g/mol

Ref: 3D-BC166806

CPI-444

Controlled Product

CAS: 1202402-40-1

Formula: C₂₀H₂₁N₇O₃

Color and Shape: Neat

Molecular weight: 407.43

Ref: TR-C781455