CAS 120279-88-1

5,6-Dihydro-6-methyl-4-oxo-4H-thieno[2,3-b]thiopyran-2-sulfonamide

Description:

5,6-Dihydro-6-methyl-4-oxo-4H-thieno[2,3-b]thiopyran-2-sulfonamide is a heterocyclic compound characterized by its unique thieno-thiopyran structure, which incorporates both sulfur and oxygen atoms in its ring system. This compound features a sulfonamide functional group, contributing to its potential biological activity, particularly in medicinal chemistry. The presence of a methyl group at the 6-position and a carbonyl group at the 4-position enhances its chemical reactivity and solubility properties. The thieno[2,3-b]thiopyran framework is known for its diverse applications, including in the development of pharmaceuticals and agrochemicals. The compound's molecular structure suggests potential interactions with biological targets, making it of interest in drug discovery. Its CAS number, 120279-88-1, allows for easy identification in chemical databases. Overall, this compound exemplifies the complexity and versatility of sulfur-containing heterocycles in organic chemistry.

Formula: C₈H₉NO₃S₃

InChI: InChI=1S/C8H9NO3S3/c1-4-2-6(10)5-3-7(15(9,11)12)14-8(5)13-4/h3-4H,2H2,1H3,(H2,9,11,12)

InChI key: InChIKey=QMNAQPMXDMLOLD-UHFFFAOYSA-N

SMILES: O=C1C2=C(SC(S(N)(=O)=O)=C2)SC(C)C1

Synonyms:

• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 5,6-dihydro-6-methyl-4-oxo-
• 5,6-dihydro-6-methyl-4-oxo-4H-thieno-[2,3,b]thiopyran-2-sulfonamide

6-Methyl-4-oxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

CAS: 120279-88-1

Formula: C₈H₉NO₃S₃

Color and Shape: Solid

Molecular weight: 263.3570

Ref: IN-DA00HFBY

6-Methyl-4-oxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

Controlled Product

CAS: 120279-88-1

Applications 6-Methyl-4-oxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide is an intermediate of Dorzolamide Hydrochloride (D535100), a carbonic anhydrase inhibitor. Antiglaucoma agent.
References Jiang, X., et. al.: Yingyong Huagong, 36, 1215 (2007); Lippa, E.A., et al.: Ophthalmology, 98, 308 (1991); Wang, R.-F., et al.: Arch. Ophthalmol., 109, 1297 (1991); Whikehart, D., et al.: J. Ocul. Pharmacol., 7, 195 (1991); Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998)

Formula: C₈H₉NO₃S₃

Color and Shape: Neat

Molecular weight: 263.36

Ref: TR-M330095

6-Methyl-4-oxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

CAS: 120279-88-1

Formula: C₈H₉NO₃S₃

Molecular weight: 263.34

Ref: ST-EA-CP-D25037