CAS 120279-89-2

4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6R)-rel-

Description:

4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6R)-rel- is a chemical compound characterized by its unique bicyclic structure that incorporates both thieno and thiopyran moieties. This compound features a sulfonamide functional group, which is known for its biological activity, particularly in medicinal chemistry. The presence of an ethylamino group contributes to its potential solubility and reactivity, while the 7,7-dioxide indicates the presence of two oxygen atoms in the sulfone group, enhancing its polar characteristics. The stereochemistry, denoted by (4R,6R)-rel-, suggests specific spatial arrangements of atoms that can influence the compound's biological interactions and pharmacological properties. This compound may exhibit various biological activities, making it of interest in pharmaceutical research, particularly in the development of therapeutics targeting specific diseases. Its structural complexity and functional groups suggest potential applications in drug design and development, although specific biological activities would require further investigation through experimental studies.

Formula: C₁₀H₁₆N₂O₄S₃

InChI: InChI=1/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/s2

InChI key: InChIKey=IAVUPMFITXYVAF-BTBXXMRTNA-N

SMILES: O=S1(=O)C2=C([C@H](NCC)C[C@H]1C)C=C(S(N)(=O)=O)S2

Synonyms:

• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, trans-
• ETS
• DORZOLAMIDE BASE
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6R)-rel-

Dorzolamide Impurity 37 (rac-Dorzolamide)

CAS: 120279-89-2

Formula: C₁₀H₁₆N₂O₄S₃

Molecular weight: 324.43

Ref: 4Z-D-6447

rac-Dorzolamide

Controlled Product

CAS: 120279-89-2

Impurity Dorzolamide EP Impurity B
Applications rac-Dorzolamide is an racemic mixture of Dorzolamide, an carbonic anhydrase inhibitor with antiglaucoma properties.
References Tarko, L., et al.: BIoorg. Med. Chem., 15, 5666 (2007); Alterio, V., et al.: Biorg. Med. Chem. Lett., 17, 4201 (2007);

Formula: C₁₀H₁₆N₂O₄S₃

Color and Shape: Neat

Molecular weight: 324.44

Ref: TR-D535145