CAS 120279-96-1: Dorzolamide

Description: Dorzolamide is a carbonic anhydrase inhibitor primarily used in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. It is a sulfonamide derivative, characterized by its ability to inhibit the enzyme carbonic anhydrase, which plays a crucial role in the production of aqueous humor in the eye. The chemical formula of dorzolamide is C10H16N2O4S, and it has a molecular weight of approximately 224.31 g/mol. This compound is typically administered as a topical ophthalmic solution, allowing for localized action with minimal systemic absorption. Dorzolamide is known for its relatively low solubility in water, which can affect its formulation and delivery. Common side effects may include ocular discomfort, taste disturbances, and allergic reactions. Its mechanism of action involves reducing bicarbonate secretion, leading to decreased fluid production in the eye, thereby lowering intraocular pressure. Overall, dorzolamide is an important therapeutic agent in managing certain eye conditions, contributing to better patient outcomes in ocular health.

Formula: C₁₀H₁₆N₂O₄S₃

InChI: InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1

InChI key: InChIKey=IAVUPMFITXYVAF-XPUUQOCRSA-N

SMILES: O=S(=O)(N)C=1SC2=C(C1)C(NCC)CC(C)S2(=O)=O

Synonyms:

• (2R,4R)-2-Ethylamino-4-Methyl-5,5-Dioxo-5,7-Dithiabicyclo[4.3.0]Nona-8,10-Diene-8-Sulfonamide
• (4R,6R)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno-[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• (4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,
• (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• 4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R-cis)-
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-cis)-
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-trans)-
• 4S,6S-Dorzolamide
• Dorzolamide(Subjecttopatentfree)
• Dorzolamide

Dorzolamide Hydrochloride

CAS: 120279-96-1130693-82-2

• Formula: C₁₀H₁₆N₂O₄S₃·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 360.89

4H-Thieno[2,3-b]thiopyran-2-sulfonamide,4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-

CAS: 120279-96-1

• Formula: C₁₀H₁₆N₂O₄S₃
• Color and Shape: Solid
• Molecular weight: 324.4400

Dorzolamide

CAS: 120279-96-1

Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.

• Formula: C₁₀H₁₆N₂O₄S₃
• Purity: 98%
• Color and Shape: White Or Almost White Crystalline Powder
• Molecular weight: 324.44

Dorzolamide

CAS: 120279-96-1

Dorzolamide is a diuretic used to treat glaucoma and ocular hypertension. It is an inhibitor …

• Formula: C₁₀H₁₆N₂O₄S₃
• Purity: Min. 95%
• Molecular weight: 324.44 g/mol