CAS 120289-23-8

Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-3-oxobutanoate

Controlled Product

CAS: 120289-23-8

Applications Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)

Formula: C₁₂H₂₀O₆

Color and Shape: Neat

Molecular weight: 260.284

Ref: TR-E951855