CAS 120293-52-9

1H-Imidazo[4,5-c]pyridine-4,6-dicarboxylicacid, 4-(2-carboxyethyl)-4,5,6,7-tetrahydro-, (4R,6S)- (9CI)

Description:

1H-Imidazo[4,5-c]pyridine-4,6-dicarboxylic acid, 4-(2-carboxyethyl)-4,5,6,7-tetrahydro-, (4R,6S)-, commonly referred to by its CAS number 120293-52-9, is a heterocyclic organic compound characterized by its imidazo and pyridine rings fused together. This compound features multiple carboxylic acid functional groups, which contribute to its acidic properties and potential for forming salts or esters. The presence of the tetrahydro structure indicates that it has a saturated ring system, which can influence its reactivity and stability. The specific stereochemistry denoted by (4R,6S) suggests that the compound has chiral centers, leading to potential enantiomeric forms that may exhibit different biological activities or pharmacological effects. This compound is of interest in medicinal chemistry and drug development due to its structural complexity and potential interactions with biological targets. Its solubility, melting point, and other physical properties would depend on the specific conditions and solvent used.

Formula: C₁₁H₁₃N₃O₆

Synonyms:

• 1H-Imidazo[4,5-c]pyridine-4,6-dicarboxylicacid, 4-(2-carboxyethyl)-4,5,6,7-tetrahydro-, (4R-cis)-
• (-)-Mikimopine

(4R,6R)-4-(2-Carboxyethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-4,6-dicarboxylic Acid

Controlled Product

CAS: 120293-52-9

Stability Hygroscopic
Applications (4R,6R)-4-(2-Carboxyethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-4,6-dicarboxylic Acid, is an isomer of Mikimopine (M385508), which forms in roots after transformation with agrobacterium and influences alkaloid production. This in turn affects insect toxicity and allelopathic properties.
References Sauerwein, M. et al.: J. Plant Physiol., 142, 446 (1993);

Formula: C₁₁H₁₃N₃O₆

Color and Shape: Neat

Molecular weight: 283.237

Ref: TR-C179210

Mikimopine

Controlled Product

CAS: 120293-52-9

Stability Hygroscopic, Unstable in Solution
Applications Mikimopine is formed in roots after transformation with agrobacterium and influences alkaloid production. This in turn affects insect toxicity and allelopathic properties.
References Sauerwein, M. et al.: J. Plant Physiol., 142, 446 (1993);

Formula: C₁₁H₁₃N₃O₆

Color and Shape: Neat

Molecular weight: 283.24

Ref: TR-M385508

Mikimopine

CAS: 120293-52-9

Mikimopine is a kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting specific proteins involved in cancer cell growth and survival, leading to apoptosis (cell death) of tumor cells. Mikimopine is an analog of a naturally occurring protein found in human urine and Chinese medicinal herbs. It specifically targets cyclin-dependent kinases, which are enzymes that regulate cell division and proliferation. This drug has shown potent anticancer activity both in vitro and in vivo, making it a promising candidate for further development as an anticancer agent. Its selectivity towards cancer cells makes it a potentially effective therapy with minimal side effects compared to traditional chemotherapy treatments.

Formula: C₁₁H₁₃N₃O₆

Purity: Min. 95%

Molecular weight: 283.24 g/mol

Ref: 3D-VEA29352