CAS 120301-02-2

2'-dehydropipecuronium

Description:

2'-Dehydropipecuronium is a chemical compound classified as a neuromuscular blocking agent, primarily used in anesthesia to facilitate muscle relaxation during surgical procedures. It is a derivative of pipecuronium, which is a non-depolarizing muscle relaxant. The compound functions by competitively inhibiting the action of acetylcholine at the neuromuscular junction, leading to temporary paralysis of skeletal muscles. Characteristically, 2'-dehydropipecuronium exhibits a longer duration of action compared to some other neuromuscular blockers, making it suitable for procedures requiring extended muscle relaxation. Its pharmacokinetics involve hepatic metabolism and renal excretion, which can influence dosing and duration of effect in patients with varying liver and kidney function. Additionally, the compound is known for its relatively low histamine release, which minimizes cardiovascular side effects. As with all neuromuscular blockers, careful monitoring of respiratory function is essential during its use to ensure patient safety.

Formula: C₃₅H₆₀Br₂N₄O₄

InChI: InChI=1/C35H60N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h13,17,26-33H,9-12,14-16,18-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27?,28?,29?,30?,31-,32-,33-,34-,35-;;/m0../s1

Synonyms:

• 2'-Dehydropipecuronium bromide
• Pyrazinium, 4-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(4,4-dimethylpiperazinium-1-yl)androstan-16-yl)-1,2,3,4-tetrahydro-1,1-dimethyl-, dibromide
• (2beta,3alpha,5alpha,8xi,9xi,14xi,17beta)-3,17-bis(acetyloxy)-16-(4,4-dimethyl-3,4-dihydropyrazin-4-ium-1(2H)-yl)-2-(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide