CAS 120373-24-2

Isopropyl Unoprostone

Description:

Isopropyl Unoprostone, with the CAS number 120373-24-2, is a synthetic compound primarily used in ophthalmology. It is an analog of prostaglandin and functions as a potent ocular hypotensive agent, meaning it helps to lower intraocular pressure, making it beneficial in the treatment of conditions such as glaucoma. The substance is characterized by its ability to enhance aqueous humor outflow, thereby reducing pressure within the eye. Isopropyl Unoprostone is typically administered as an eye drop formulation. Its chemical structure includes a branched isopropyl group, contributing to its pharmacological properties. The compound is generally well-tolerated, although potential side effects may include ocular irritation or hyperemia. As with many pharmaceuticals, its use should be guided by a healthcare professional, considering individual patient needs and potential interactions with other medications. Overall, Isopropyl Unoprostone represents a significant advancement in the management of elevated intraocular pressure.

Formula: C₂₅H₄₄O₅

InChI: InChI=1/C25H44O5/c1-4-5-6-7-10-13-20(26)16-17-22-21(23(27)18-24(22)28)14-11-8-9-12-15-25(29)30-19(2)3/h8,11,19,21-24,27-28H,4-7,9-10,12-18H2,1-3H3/b11-8+/t21-,22-,23+,24-/m1/s1

InChI key: InChIKey=XXUPXHKCPIKWLR-JHUOEJJVSA-N

SMILES: C(CC(CCCCCCC)=O)[C@@H]1[C@@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](O)C[C@H]1O

Synonyms:

• 1-methylethyl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoate (non-preferred name)
• 1-methylethyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoate (non-preferred name)
• 13,14-Dihydro-15-keto-20-ethyl-PG F_2α isopropyl ester
• 13,14-Dihydro-15-keto-20-ethyl-PGF2
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, 1-methylethyl ester, (5Z)-
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, 1-methylethyl ester, [1R-[1α(Z),2β,3α,5α]]-
• Rescula
• Uf 021
• Unoprostone isopropyl ester
• Isopropyl unoprostone
• 13,14-dihydro-15-keto-20-ethyl-pgf
• Rescul
• 9ALPHA,11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID, ISOPROPYL ESTER
• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopenthyl]-5-heptenoic Acid Isopropyl Ester
• 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER

Unoprostone isopropyl ester

CAS: 120373-24-2

Formula: C₂₅H₄₄O₅

Purity: 95%

Color and Shape: Liquid

Molecular weight: 424.6139

Ref: IN-DA007Q2P

Unoprostone-d15 Isopropyl Ester

Controlled Product

CAS: 120373-24-2

Formula: C₂₅D₁₅H₂₉O₅

Color and Shape: Neat

Molecular weight: 439.706

Ref: TR-U800052

Unoprostone Isopropyl Ester

Controlled Product

CAS: 120373-24-2

Applications Antiglaucoma; used in treatment of ocular hypertension.
References Goh, Y., et al.: Jpn. J. Ophthalmol., 38, 236 (1994), Nordmann, J.-P., et al.: Am. J. Ophthalmol., 133, 1 (2002),

Formula: C₂₅H₄₄O₅

Color and Shape: Neat

Molecular weight: 424.61

Ref: TR-U800050

Unoprostone isopropyl

CAS: 120373-24-2

Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.

Formula: C₂₅H₄₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 424.61

Ref: TM-T20644