CAS 120373-36-6

Unoprostone

Description:

Unoprostone, with the CAS number 120373-36-6, is a synthetic prostaglandin analog primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. Unoprostone is characterized by its ability to mimic the effects of natural prostaglandins, promoting vasodilation and enhancing blood flow to the optic nerve. The substance is typically administered as an eye drop solution and is known for its relatively favorable side effect profile compared to other glaucoma medications. Its chemical structure includes a bicyclic framework, which contributes to its biological activity. Unoprostone is also noted for its stability and effectiveness in long-term treatment regimens. As with any medication, it is essential to consider potential interactions and contraindications, particularly in patients with specific ocular conditions or those taking other medications. Overall, unoprostone represents a valuable option in the management of elevated intraocular pressure.

Formula: C₂₂H₃₈O₅

InChI: InChI=1S/C22H38O5/c1-2-3-4-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27/h6,9,18-21,24-25H,2-5,7-8,10-16H2,1H3,(H,26,27)/b9-6-/t18-,19-,20+,21-/m1/s1

InChI key: InChIKey=TVHAZVBUYQMHBC-SNHXEXRGSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](CCC(CCCCCCC)=O)[C@H](O)C[C@@H]1O

Synonyms:

• (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid (non-preferred name)
• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid
• (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid (non-preferred name)
• (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid
• 13,14-Dihydro-15-Keto-20-Ethyl Prostaglandin F2Alpha
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, [1R-[1α(Z),2β,3α,5α]]-
• 9Alpha, 11Alpha-Dihydroxy-15-Oxo-20A,20B-Dihomoprost-5-En-1-Oic Acid
• Unoprostone

Unoprostane

Controlled Product

CAS: 120373-36-6

Formula: C₂₂H₃₈O₅

Color and Shape: Neat

Molecular weight: 382.534

Ref: TR-U847060

Unoprostone

CAS: 120373-36-6

Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.

Formula: C₂₂H₃₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 382.53

Ref: TM-T13955