CAS 120410-24-4: Biapenem

Description: Biapenem is a broad-spectrum carbapenem antibiotic, primarily used for the treatment of various bacterial infections. It exhibits a high degree of stability against many beta-lactamases, making it effective against a wide range of Gram-positive and Gram-negative bacteria, including some strains resistant to other antibiotics. Biapenem works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is typically administered intravenously and is known for its favorable pharmacokinetic profile, including good tissue penetration and a relatively short half-life. The compound is generally well-tolerated, but like other antibiotics, it may cause side effects such as gastrointestinal disturbances or allergic reactions. Biapenem is particularly valuable in clinical settings for treating complicated infections, including those caused by multi-drug resistant organisms. Its use is often guided by susceptibility testing to ensure effectiveness against the specific pathogens involved in an infection. As with all antibiotics, appropriate use is crucial to minimize the development of resistance.

Formula: C₁₅H₁₈N₄O₄S

InChI: InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1

InChI key: InChIKey=MRMBZHPJVKCOMA-YJFSRANCSA-N

SMILES: O=C([O-])C1=C(SC2CN3C=NC=[N+]3C2)C(C)C4N1C(=O)C4C(O)C

Synonyms:

• (4R,5S,6S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
• 1-Azabicyclo[3.2.0]heptane, 5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium deriv.
• 5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium, 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-, inner salt
• 5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium, 6-[[2-carboxy-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-, inner salt, [4R-[4α,5β,6β(R*)]]-
• 6-({(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl}sulfanyl)-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium
• 6-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-Hydroxyethyl]-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-En-3-Yl]Thio]-6,7-Dihydro-5H-Pyrazolo[1,2-A][1,2,4]Triazol-4-Ium Inner Salt
• 6-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a]-s-triazol-4-ium hydroxide, inner salt
• Biapenern
• Cl 186-815
• Cl 186815
• L 627
• Ljc 10627
• Omegacin

Biapenem

CAS: 120410-24-4

• Formula: C₁₅H₁₈N₄O₄S
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 350.39

5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium, 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-, inner salt

CAS: 120410-24-4

• Formula: C₁₅H₁₈N₄O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 350.3928

(4R,5S,6S)-3-((6,7-Dihydro-5H-Pyrazolo[1,2-A][1,2,4]Triazol-4-Ium-6-Yl)Thio)-6-((R)-1-Hydroxyethyl)-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylate

CAS: 120410-24-4

• Purity: 98%
• Molecular weight: 350.39g/mol

Biapenem

CAS: 120410-24-4

• Formula: C₁₅H₁₈N₄O₄S
• Purity: ≥ 98.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 350.39

Biapenem

CAS: 120410-24-4

• Purity: ≥95%
• Molecular weight: 350.39g/mol

Biapenem-13C2,15N2

CAS: 120410-24-4

• Formula: C₁₃₁₃C₂H₁₈N₂₁₅N₂O₄S
• Molecular weight: 354.36

Biapenem

CAS: 120410-24-4

• Formula: C₁₅H₁₈N₄O₄S
• Molecular weight: 350.39

Biapenem-13C2,15N3

CAS: 120410-24-4

• Formula: C₁₃₁₃C₂H₁₈N₁₅N₃O₄S
• Molecular weight: 355.36

Biapenem-15N3

CAS: 120410-24-4

• Formula: C₁₅H₁₈N₁₅N₃O₄S
• Molecular weight: 353.37

Biapenem

CAS: 120410-24-4

Biapenem (CLI 86815), a carbapenem antibiotic, has broad antibacterial effects, stable kidney enzyme resistance, and …

• Formula: C₁₅H₁₈N₄O₄S
• Purity: 97.92%
• Color and Shape: White To Light Yellow Powder
• Molecular weight: 350.39

Biapenem

CAS: 120410-24-4

Please enquire for more information about Biapenem including the price, delivery time and more detailed …

• Formula: C₁₅H₁₈N₄O₄S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 350.39 g/mol

Biapenem

CAS: 120410-24-4

Applications An carbapenem antibacterial. References Shigemi, A., et al.: Int. J. Antimicrob. Agents, 34, 589 …

• Formula: C₁₅H₁₈N₄O₄S
• Color and Shape: Neat
• Molecular weight: 350.39