CAS 120443-16-5: Verlukast

Description:Verlukast, with the CAS number 120443-16-5, is a chemical compound that belongs to the class of leukotriene receptor antagonists. It is primarily utilized in the treatment of asthma and allergic rhinitis by inhibiting the action of leukotrienes, which are inflammatory mediators that contribute to bronchoconstriction and mucus production. The compound is characterized by its ability to selectively block the cysteinyl leukotriene receptor, thereby reducing airway inflammation and improving respiratory function. Verlukast is typically administered orally and is known for its favorable pharmacokinetic profile, including good bioavailability and a relatively long half-life, which allows for once-daily dosing. Its safety profile is generally well-tolerated, with common side effects being mild and transient. As with other medications in its class, it is important for patients to consult healthcare professionals for appropriate use and potential interactions with other medications. Overall, Verlukast represents a valuable option in the management of respiratory conditions associated with leukotriene activity.

Formula:C₂₆H₂₇ClN₂O₃S₂

InChI:InChI=1/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+

Synonyms:
Verlukast [USAN:INN]
3-(((alphaR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-alpha-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic acid
L 668,019
Mk 679
Propanoic acid, 3-(((3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)-, (R-(E))-
Unii-5Q9O54P0H7
Verlukastum
Verlukastum [INN-Latin]

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Verlukast REF: TR-V128500CAS: 120443-16-5	- - -	249.00 €~802.00 €	Thu 13 Mar 25
Verlukast REF: 3D-FV28691CAS: 120443-16-5	Min. 95%	To inquire	Mon 14 Apr 25
Verlukast REF: TM-T19674CAS: 120443-16-5	98%	717.00 €~1,084.00 €	Mon 21 Apr 25