CAS 120511-73-1: Anastrozole

Description:Anastrozole is a non-steroidal aromatase inhibitor primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Its mechanism of action involves the inhibition of the aromatase enzyme, which is responsible for converting androgens into estrogens, thereby reducing estrogen levels in the body. This reduction is crucial as many breast cancers are fueled by estrogen. Anastrozole is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life, allowing for once-daily dosing. Common side effects may include hot flashes, joint pain, and fatigue, among others. The substance is classified as a prescription medication and is often part of adjuvant therapy following surgery or radiation. Anastrozole is recognized for its effectiveness in improving disease-free survival rates in breast cancer patients, making it a significant option in oncological pharmacotherapy. Its chemical structure features a triazole ring, contributing to its specificity and efficacy as an aromatase inhibitor.

Formula:C₁₇H₁₉N₅

InChI:InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3

InChI key:InChIKey=YBBLVLTVTVSKRW-UHFFFAOYSA-N

SMILES:N#CC(C1=CC(=CC(=C1)C(C#N)(C)C)CN2N=CN=C2)(C)C

Synonyms:
1,3-Benzenediacetonitrile, α1,α1,α3,α3-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
1,3-Benzenediacetonitrile,Alpha,Alpha,Alpha',Alpha'-Tetramethyl-5-(1H-1,2,4-Triazol-1-Ylmethyl)-
1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
1-[3,5-Di-(1-Methyl-1-Cyano)-Ethyl]-Benzyl-1,2,4-Triazole
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2,2′-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile)
2-[3-(1-Cyano-1-methylethyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]-2-methylpropanenitrile
2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile
2-[3-(2-Cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
Anastrazole
See more synonyms
Anastrol
Anastrozol
Anatrozole
Arimidex
Ici-D-1033
Tetramethyl-5-(1H-1,2,4-Triazol-1Ylmethyl) 1,3-Benzenediacetionitrile
Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetionitrile
ZD-1033, ICI-D-1033, Arimidex
Zd
Zd-1033
α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Anastrozole
1,3-Benzenediacetonitrile, α1,α1,α3,α3-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
1,3-benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl- 5-(1h-1,2,4-triazol-1-ylmethyl)-
zd
α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Anastrozole REF: 3B-A2370CAS: 120511-73-1	>98.0%(T)(HPLC)	30.00 €	Mon 17 Mar 25
Anastrozole REF: 47-1213CAS: 120511-73-1	99.7%	242.00 €	Mon 24 Mar 25
Anastrozole CRS REF: 41-Y0001522CAS: 120511-73-1	- - -	115.00 €	Mon 24 Mar 25
Anastrozole REF: 45-1034807CAS: 120511-73-1	- - -	736.00 €	Tue 25 Mar 25
Anastrozole REF: TM-T0393CAS: 120511-73-1	99.73% - 99.84%	49.00 €~118.00 €	Mon 24 Mar 25
Anastrozole REF: 4Z-A-241CAS: 120511-73-1	- - -	To inquire	Tue 25 Mar 25
Anastrozole REF: 04-C10248750CAS: 120511-73-1	- - -	130.00 €	Thu 27 Mar 25
Anastrozole, 98% REF: AC-46097CAS: 120511-73-1	98%	To inquire	Thu 27 Mar 25
Anastrozole REF: 86-MM1250.00CAS: 120511-73-1	- - -	301.00 €	Thu 27 Mar 25
Anastrozole REF: 7W-GP2172CAS: 120511-73-1	≥ 98.0%	93.00 €~192.00 €	Mon 31 Mar 25
Anastrozole RS REF: 2K-1007500021CAS: 120511-73-1	- - -	To inquire	Tue 01 Apr 25
Anastrozole REF: TR-A637425CAS: 120511-73-1	- - -	106.00 €~264.00 €	Thu 03 Apr 25
Anastrozole - Bio-X ™ REF: 3D-BT164176CAS: 120511-73-1	Min. 95%	145.00 €	Fri 04 Apr 25
Anastrozole REF: 3D-FT10600CAS: 120511-73-1	Min. 98 Area-%	139.00 €~1,875.00 €	Fri 04 Apr 25