CAS 1205548-04-4

2-[4-(Dimethylamino)phenyl]-7,8-dihydroxy-4H-1-benzopyran-4-one

Description:

2-[4-(Dimethylamino)phenyl]-7,8-dihydroxy-4H-1-benzopyran-4-one, also known by its CAS number 1205548-04-4, is a synthetic organic compound characterized by its complex structure, which includes a benzopyran core with hydroxyl groups and a dimethylamino substituent. This compound typically exhibits properties such as solubility in organic solvents and potential biological activity, making it of interest in medicinal chemistry. The presence of hydroxyl groups suggests it may participate in hydrogen bonding, influencing its reactivity and interaction with biological targets. The dimethylamino group can enhance its lipophilicity, potentially affecting its pharmacokinetics. Additionally, compounds of this type may exhibit antioxidant properties due to the presence of phenolic hydroxyl groups. Overall, the unique structural features of this compound contribute to its potential applications in pharmaceuticals, particularly in the development of therapeutic agents. Further studies would be necessary to fully elucidate its biological activities and mechanisms of action.

Formula: C₁₇H₁₅NO₄

InChI: InChI=1S/C17H15NO4/c1-18(2)11-5-3-10(4-6-11)15-9-14(20)12-7-8-13(19)16(21)17(12)22-15/h3-9,19,21H,1-2H3

InChI key: InChIKey=YPAYCZOHGRSGJS-UHFFFAOYSA-N

SMILES: OC1=C2C(C(=O)C=C(O2)C3=CC=C(N(C)C)C=C3)=CC=C1O

Synonyms:

• 7,8-Dihydroxy-2-[4-(dimethylamino)phenyl]-4H-chromen-4-one
• 2-[4-(Dimethylamino)phenyl]-7,8-dihydroxy-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 2-[4-(dimethylamino)phenyl]-7,8-dihydroxy-
• 2-4dimethylaminophenyl-78-Dihydroxyflavone
• 2-[4-(dimethylamino)phenyl]-7,8-dihydroxychromen-4-one

4'-Dimethylamino 7,8-Dihydroxyflavone

Controlled Product

CAS: 1205548-04-4

Applications 4'-Dimethylamino 7,8-Dihydroxyflavone is a synthetic 7,8-Dihydroxyflavone derivative which promotes neurogenesis and exhibits potent antidepressant effect. The 7,8-dihydroxy groups are essential for the agonistic effect. 4'-Dimethylamino 7,8-Dihydroxyflavone displays higher TrkB agonistic activity than that of 7,8-Dihydroxyflavone (D452830).
References Thoenen, H., et al.: Trends Neurosci., 14, 165 (1991); Nibuya, M., et al.: J. Neurosci., 15, 7539 (1995); Kaplan, D., et al.: Curr. Opin. Neurobiol., 10, 381 (2000); Saarelainen, T., et al.: J. Neurosci., 2003, 23, 349 (2003);

Formula: C₁₇H₁₅NO₄

Color and Shape: Neat

Molecular weight: 297.31

Ref: TR-D461140