CBZ-AEP, or Carbobenzyloxy-Aminoethylpyridine, is a chemical compound characterized by its unique structure that includes a carbobenzyloxy group and an aminoethylpyridine moiety. This compound is typically used in organic synthesis and medicinal chemistry, often serving as an intermediate in the preparation of various pharmaceuticals. CBZ-AEP is known for its ability to participate in reactions such as amide bond formation and can act as a protecting group for amines due to the stability of the carbobenzyloxy group under certain conditions. Its solubility properties may vary depending on the solvent used, and it is generally handled with care due to potential reactivity. The compound's molecular structure contributes to its biological activity, making it a subject of interest in drug development. As with many chemical substances, safety data sheets should be consulted for handling and storage guidelines to ensure safe laboratory practices.

3-[2-(Cbz-amino)ethoxy]propanoic acid is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.

CBZ-AEP

1205751-19-4: CBZ-AEP, or Carbobenzyloxy-Aminoethylpyridine, is a chemical compound characterized by its unique structure that includes a carbobenzyloxy group and an aminoethylpyridine moiety. This compound is typically used in organic synthesis and medicinal chemistry, often serving as an intermediate in the preparation of various pharmaceuticals. CBZ-AEP is known for its ability to participate in reactions such as amide bond formation and can act as a protecting group for amines due to the stability of the carbobenzyloxy group under certain conditions. Its solubility properties may vary depending on the solvent used, and it is generally handled with care due to potential reactivity. The compound's molecular structure contributes to its biological activity, making it a subject of interest in drug development. As with many chemical substances, safety data sheets should be consulted for handling and storage guidelines to ensure safe laboratory practices.

3-[2-(Cbz-amino)ethoxy]propanoic acid

Cbz-NH-PEG1-CH2CH2COOH

<p>Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.</p>

CAS 1205751-19-4

CBZ-AEP

3-[2-(Cbz-amino)ethoxy]propanoic acid

Ref: IN-DA01JLPU

Cbz-NH-PEG1-CH2CH2COOH

Ref: 54-BUP17434

Cbz-NH-PEG1-CH2CH2COOH

Ref: TM-T17716

Cbz-NH-PEG1-CH2CH2COOH

Ref: 10-F554861