CAS 1206102-10-4

(4R,12aS)-7-(benzyloxy)-9-bromo-4-methyl-3,4,12,12a-tetrahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-6,8-dione

Description:

The chemical substance with the name "(4R,12aS)-7-(benzyloxy)-9-bromo-4-methyl-3,4,12,12a-tetrahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-6,8-dione" and CAS number "1206102-10-4" is a complex organic compound characterized by its unique bicyclic structure, which incorporates multiple functional groups, including a benzyloxy group and bromine atom. This compound features a tetrahydro-pyrido structure fused with a pyrazino and oxazine moiety, contributing to its potential biological activity. The presence of the bromine atom suggests possible reactivity and interactions in various chemical environments. The stereochemistry indicated by the (4R,12aS) configuration implies specific spatial arrangements of atoms, which can influence the compound's pharmacological properties. Such compounds are often investigated for their potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. The intricate structure and functional groups may also suggest interesting properties related to solubility, stability, and reactivity, making it a subject of interest in both synthetic and medicinal chemistry research.

Formula: C₁₉H₁₉BrN₂O₄

Synonyms:

• (4R,12aS)-7-(benzyloxy)-9-bromo-4-methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione
• (4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-6,8-dione
• (4R,12AS)-7-(BENZYLOXY)-9-BROMO-4-METHYL-3,4,12,12A-TETRAHYDRO-2H-PYRIDO[1,2:4,5]PYRAZINO[2,1-B][1,3]OXAZINE-6,8-DIONE
• 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-6,8-dione, 9-bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-, (4R,12aS)-

(4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-d2-6,8-dione

Controlled Product

CAS: 1206102-10-4

Applications (4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-d2-6,8-dione is an isotope labelled intermediate of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.

Formula: C₁₉D₂H₁₇BrN₂O₄

Color and Shape: Neat

Molecular weight: 421.281

Ref: TR-B688272