CAS 120615-25-0
:N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide
Description:
N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide, identified by its CAS number 120615-25-0, is a chemical compound that features a sulfonamide functional group, which is known for its antibacterial properties. This compound contains an isoquinoline moiety, contributing to its potential biological activity, particularly in medicinal chemistry. The presence of the aminoethyl group suggests that it may interact with biological targets through hydrogen bonding or ionic interactions. The chlorine substituent at the 5-position of the isoquinoline ring can influence the compound's lipophilicity and overall reactivity. This compound may exhibit properties such as solubility in polar solvents, and its structure suggests potential applications in drug development, particularly in targeting specific enzymes or receptors. Additionally, the sulfonamide group is often associated with a range of pharmacological activities, including antimicrobial and antitumor effects. Overall, N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide represents a compound of interest in the field of pharmaceutical research.
Formula:C11H12ClN3O2S
InChI:InChI=1S/C11H12ClN3O2S/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10/h1-3,5,7,15H,4,6,13H2
InChI key:InChIKey=OGKYMFFYOWUTKV-UHFFFAOYSA-N
SMILES:S(NCCN)(=O)(=O)C=1C2=C(C(Cl)=CC1)C=CN=C2
Synonyms:- 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro-
- 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro- Dihydrochloride
- N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide
- N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
- CKI 7
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Found 3 products.
CKI-7 free base
CAS:CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H12ClN3O2SColor and Shape:SolidMolecular weight:285.75N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide
CAS:<p>N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide</p>Formula:C11H12ClN3O2SPurity:≥95%Color and Shape: pale yellow solidMolecular weight:285.75g/molN-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
CAS:Controlled Product<p>Applications Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hidaka, H., et al.: J. Biol. Chem., 264, 9, 4924 (1989)<br></p>Formula:C11H12ClN3O2SColor and Shape:NeatMolecular weight:285.75


