CAS: 1206161-97-8 - Filgotinib

Formula: C₂₁H₂₃N₅O₃S

InChI: InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)

InChI key: InChIKey=RIJLVEAXPNLDTC-UHFFFAOYSA-N

SMILES: O=C(NC=1N=C2C=CC=C(C=3C=CC(=CC3)CN4CCS(=O)(=O)CC4)N2N1)C5CC5

Synonyms:

• N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
• filgotinib (GLPG0634)
• G 146034
• GLPG 0634
• Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-
• CyclopropanecarboxaMide, N-[5-[4-[(1,1-dioxido-4-thioMorpholinyl)Methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-
• Filgotinib
• N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• SYN1158

N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

CAS: 1206161-97-8

• Formula: C₂₁H₂₃N₅O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 425.5040

Filgotinib-d4

CAS: 1206161-97-82041095-50-3

• Formula: C₂₁H₁₉D₄N₅O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 429.53

Filgotinib

CAS: 1206161-97-8

• Formula: C₂₁H₃₅N₅O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 425.51

Filgotinib

CAS: 1206161-97-8

• Molecular weight: 425.50g/mol

GLPG0634

CAS: 1206161-97-8

Filgotinib

CAS: 1206161-97-8

Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and …

• Formula: C₂₁H₂₃N₅O₃S
• Purity: 98.03% - ≥95%
• Color and Shape: Solid
• Molecular weight: 425.5

GLPG-0634 (Filgotinib)

CAS: 1206161-97-8

Applications GLPG-0634 (Filgotinib) is a potent, selective JAK1 inhibitor. Used as an anti-inflammatory agent, it …

• Formula: C₂₁H₂₃N₅O₃S
• Color and Shape: Neat
• Molecular weight: 425.5

Filgotinib

CAS: 1206161-97-8

Filgotinib is an investigational drug that blocks the activity of the Janus kinase (JAK) family …

• Formula: C₂₁H₂₃N₅O₃S
• Purity: Min. 95%
• Molecular weight: 425.51 g/mol