CAS 120635-74-7: Cilansetron

Description: Cilansetron is a chemical compound primarily recognized for its role as a selective serotonin 5-HT3 receptor antagonist. It is often investigated for its potential therapeutic applications in treating gastrointestinal disorders, particularly irritable bowel syndrome (IBS). The molecular structure of cilansetron includes a piperidine ring, which contributes to its pharmacological activity. As a 5-HT3 receptor antagonist, cilansetron works by inhibiting the action of serotonin at these receptors, which can help alleviate symptoms such as abdominal pain and discomfort associated with IBS. Cilansetron is characterized by its moderate solubility in water and its stability under standard conditions. Its pharmacokinetics involve oral administration, with a focus on its absorption, distribution, metabolism, and excretion profiles. While cilansetron has shown promise in clinical studies, its availability and approval status may vary by region, and ongoing research continues to explore its efficacy and safety in various patient populations.

Formula: C₂₀H₂₁N₃O

InChI: InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3/t15-/m1/s1

InChI key: InChIKey=NCNFDKWULDWJDS-OAHLLOKOSA-N

SMILES: O=C1C=2C=3C=CC=C4C3N(C2CCC1CN5C=CN=C5C)CCC4

Synonyms:

• 4H-Pyrido[3,2,1-jk]carbazol-11(8H)-one, 5,6,9,10-tetrahydro-10-[(2-methyl-1H-imidazol-1-yl)methyl]-, (R)-
• (10R)-10-[(2-methyl-1H-imidazol-1-yl)methyl]-5,6,9,10-tetrahydro-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one
• (10R)-5,6,9,10-Tetrahydro-10-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one
• Cilansetron [USAN:INN]
• Cilansetron
• (-)-(R)-5,6,9,10-Tetrahydro-10-((2-methylimidazol-1-yl)methyl)-4H-pyrido(3,2,1-jk)carbazol-11(8H)-one
• 10-[(2-methyl-1H-imidazol-1-yl)methyl]-5,6,9,10-tetrahydro-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one
• 4H-Pyrido(3,2,1-jk)carbazol-11(8H)-one, 5,6,9,10-tetrahydro-10-((2-methyl-1H-imidazol-1-yl)methyl)-, (R)-
• KC-9946
• UNII-2J6DQ1U5B5
• 4H-Pyrido[3,2,1-jk]carbazol-11(8H)-one, 5,6,9,10-tetrahydro-10-[(2-methyl-1H-imidazol-1-yl)methyl]-, (10R)-

Cilansetron

CAS: 120635-74-7

Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related …

• Formula: C₂₀H₂₁N₃O
• Purity: 99.77% - 99.85%
• Color and Shape: Solid
• Molecular weight: 319.4