CAS 1206524-86-8

MK 5172 potassiuM salt

Description:

MK-5172, also known as MK-5172 potassium salt, is a potent and selective inhibitor of the hepatitis C virus (HCV) NS3/4A protease, which plays a crucial role in the viral replication process. This compound is part of a class of antiviral agents known as direct-acting antivirals (DAAs). Its chemical structure features a complex arrangement that contributes to its high specificity and efficacy against HCV. MK-5172 is typically administered in combination with other antiviral medications to enhance therapeutic outcomes and reduce the risk of resistance. The potassium salt form improves its solubility and bioavailability, making it more effective for oral administration. In clinical studies, MK-5172 has demonstrated a favorable safety profile, with common side effects being mild to moderate. Its development represents a significant advancement in the treatment of chronic hepatitis C, offering hope for improved patient outcomes and potential cure rates. As with all pharmaceuticals, its use should be guided by healthcare professionals, considering individual patient factors and potential drug interactions.

Formula: C₃₈H₄₉N₆O₉S·K

Synonyms:

• Grazoprevir (MK-5172) potassium salt
• MK5172 potassiuM salt
• MK-5172 (potassiuM salt)
• GRAZOPREVIR POTASSIUM SALT;MK5172 POTASSIUM SALT;MK 5172 POTASSIUM SALT
• Grazoprevir potassiuM salt
• 2)-ether potassium salt (1:1)
• (1R,2S)-N-[[[(1R,2R)-2-[5-(3-Hydroxy-6-methoxy-2-quinoxalinyl)pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenylcCyclopropanecarboxamide cyclic (1-2)-ether potassium salt (1:1)
• Grazoprevir potassium
• MK-5172 Potassium
• MK 5172 potassiuM salt

Grazoprevir potassium salt

CAS: 1206524-86-8

Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.

Formula: C₃₈H₄₉KN₆O₉S

Color and Shape: Solid

Molecular weight: 805

Ref: TM-T19948

Grazoprevir potassium salt

CAS: 1206524-86-8

Grazoprevir is a hepatitis C virus (HCV) protease inhibitor. It binds to the active site of HCV protease, inhibiting its function and preventing the cleavage of viral polyprotein into functional proteins. Grazoprevir has been shown to be effective in reducing HCV RNA levels in patients with chronic kidney disease. Grazoprevir also appears to have a favorable safety profile and is well tolerated.

Formula: C₃₈H₄₉KN₆O₉S

Purity: Min. 95%

Molecular weight: 804.99 g/mol

Ref: 3D-GYB52486