CAS 120658-63-1
:N(alpha)fmoc-N(gamma)(2,4,6-trimethoxy-benzyl)-L-asparagine
Description:
N(alpha)-Fmoc-N(gamma)(2,4,6-trimethoxy-benzyl)-L-asparagine is a derivative of the amino acid L-asparagine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group at the alpha-amino group and a 2,4,6-trimethoxybenzyl group at the gamma-carboxyl group. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective group that can be selectively removed under basic conditions. The presence of the trimethoxybenzyl group enhances the compound's hydrophobicity and can influence the solubility and reactivity of the amino acid during synthesis. The structure contributes to its stability and compatibility with various coupling reagents used in peptide formation. Additionally, the compound's unique functional groups may impart specific interactions in biological systems, making it of interest in medicinal chemistry and drug design. Overall, this compound exemplifies the complexity and versatility of amino acid derivatives in synthetic chemistry.
Formula:C2H30N2O8
Synonyms:- Fmoc-Asn(Tmob)-OH
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