CAS 1206880-66-1

5-[[(2S)-1-Acetyl-2,3-dihydro-1H-indol-2-yl]methoxy]-3-[(1,1-dimethylethyl)thio]-1-[[4-(5-methoxy-2-pyrimidinyl)phenyl]methyl]-α,α-dimethyl-1H-indole-2-propanoic acid

Description:

The chemical substance with the name "5-[[[2S]-1-Acetyl-2,3-dihydro-1H-indol-2-yl]methoxy]-3-[(1,1-dimethylethyl)thio]-1-[[4-(5-methoxy-2-pyrimidinyl)phenyl]methyl]-α,α-dimethyl-1H-indole-2-propanoic acid" and CAS number "1206880-66-1" is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as indole, methoxy, and thioether moieties. This compound is likely to exhibit significant biological activity due to its structural features, which may interact with various biological targets. It may possess properties such as lipophilicity, which can influence its absorption and distribution in biological systems. The presence of the acetyl group suggests potential for metabolic transformation, while the pyrimidine and phenyl components may contribute to its pharmacological profile. Overall, this compound's unique characteristics make it a subject of interest in medicinal chemistry and drug development, particularly in the context of exploring its therapeutic potential. Further studies would be necessary to elucidate its specific properties and biological effects.

Formula: C₄₀H₄₄N₄O₅S

InChI: InChI=1S/C40H44N4O5S/c1-25(45)44-29(18-28-10-8-9-11-33(28)44)24-49-30-16-17-34-32(19-30)36(50-39(2,3)4)35(20-40(5,6)38(46)47)43(34)23-26-12-14-27(15-13-26)37-41-21-31(48-7)22-42-37/h8-17,19,21-22,29H,18,20,23-24H2,1-7H3,(H,46,47)/t29-/m0/s1

InChI key: InChIKey=VYXWHVDEWWHDLH-LJAQVGFWSA-N

SMILES: C(N1C=2C(C(SC(C)(C)C)=C1CC(C(O)=O)(C)C)=CC(OC[C@H]3N(C(C)=O)C=4C(C3)=CC=CC4)=CC2)C5=CC=C(C=C5)C=6N=CC(OC)=CN6

Synonyms:

• (S)-3-(5-((1-Acetylindolin-2-yl)methoxy)-3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid
• 1H-Indole-2-propanoic acid, 5-[[(2S)-1-acetyl-2,3-dihydro-1H-indol-2-yl]methoxy]-3-[(1,1-dimethylethyl)thio]-1-[[4-(5-methoxy-2-pyrimidinyl)phenyl]methyl]-α,α-dimethyl-
• AM 679
• 5-[[(2S)-1-Acetyl-2,3-dihydro-1H-indol-2-yl]methoxy]-3-[(1,1-dimethylethyl)thio]-1-[[4-(5-methoxy-2-pyrimidinyl)phenyl]methyl]-α,α-dimethyl-1H-indole-2-propanoic acid

AM679

CAS: 1206880-66-1

AM679 is a potent, selective FLAP inhibitor with strong leukotriene suppression in vivo, minimal CYP3A4 interaction, and excellent pharmacokinetics in rodent models.

Formula: C₄₀H₄₄N₄O₅S

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 692.87

Ref: TM-T14205