CAS 1207283-85-9

N-[(5aR,6aS,7S,10aS)-9-(Aminocarbonyl)-7-(dimethylamino)-4-fluoro-5,5a,6,6a,7,10,10a,12-octahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-2-naphthacenyl]-1-pyrrolidineacetamide

Description:

N-[(5aR,6aS,7S,10aS)-9-(Aminocarbonyl)-7-(dimethylamino)-4-fluoro-5,5a,6,6a,7,10,10a,12-octahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-2-naphthacenyl]-1-pyrrolidineacetamide, with CAS number 1207283-85-9, is a complex organic compound characterized by its multi-ring structure and various functional groups. It features a naphthacene backbone, which contributes to its potential biological activity. The presence of an aminocarbonyl group suggests it may participate in hydrogen bonding and other interactions, enhancing its solubility and reactivity. The dimethylamino group indicates basic properties, which could influence its pharmacokinetics and interaction with biological targets. Additionally, the fluorine atom may enhance its metabolic stability and lipophilicity. The compound's stereochemistry, indicated by the specific configuration at multiple chiral centers, is crucial for its biological activity, potentially affecting receptor binding and efficacy. Overall, this substance may have applications in medicinal chemistry, particularly in the development of therapeutic agents, although specific biological activities would require further investigation.

Formula: C₂₇H₃₁FN₄O₈

InChI: InChI=1S/C27H31FN4O8/c1-31(2)20-13-8-11-7-12-14(28)9-15(30-16(33)10-32-5-3-4-6-32)21(34)18(12)22(35)17(11)24(37)27(13,40)25(38)19(23(20)36)26(29)39/h9,11,13,20,34,36-37,40H,3-8,10H2,1-2H3,(H2,29,39)(H,30,33)/t11-,13-,20-,27-/m0/s1

InChI key: InChIKey=HLFSMUUOKPBTSM-ISIOAQNYSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C(C3)=C(F)C=C(NC(CN5CCCC5)=O)C4O)[H])[H]

Synonyms:

• 1-Pyrrolidineacetamide, N-[(5aR,6aS,7S,10aS)-9-(aminocarbonyl)-7-(dimethylamino)-4-fluoro-5,5a,6,6a,7,10,10a,12-octahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-2-naphthacenyl]-
• TP-434
• N-[(5aR,6aS,7S,10aS)-9-(Aminocarbonyl)-7-(dimethylamino)-4-fluoro-5,5a,6,6a,7,10,10a,12-octahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-2-naphthacenyl]-1-pyrrolidineacetamide
• Xerava
• Eravacycline

Eravacycline

CAS: 1207283-85-9

Formula: C₂₇H₃₁FN₄O₈

Molecular weight: 558.56

Ref: 4Z-T-109036

Eravacycline

CAS: 1207283-85-9

Eravacycline is an antimicrobial agent that inhibits bacterial growth by binding to the 30S ribosomal subunit and inhibiting protein synthesis. Eravacycline has been shown to be effective against a wide variety of Gram-positive and Gram-negative bacteria, including multidrug-resistant strains. This drug binds to the 16S RNA in the ribosome, which is responsible for decoding messenger RNA. Eravacycline is also active against Mycoplasma pneumoniae and Chlamydia trachomatis. It has been shown to be well tolerated in humans, with mild diarrhea being the most common adverse effect.

Formula: C₂₇H₃₁FN₄O₈

Purity: Min. 95%

Molecular weight: 558.56 g/mol

Ref: 3D-FD136890

Eravacycline

CAS: 1207283-85-9

Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.

Formula: C₂₇H₃₁FN₄O₈

Purity: 97.46%

Color and Shape: Solid

Molecular weight: 558.56

Ref: TM-T11227