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CAS 120791-76-6

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NALPHA-FMOC-L-THREONINE TERT-BUTYL ESTER

Description:
NALPHA-FMOC-L-THREONINE TERT-BUTYL ESTER is a protected amino acid derivative commonly used in peptide synthesis. It features a tert-butyl ester group that enhances its stability and solubility, making it suitable for various organic reactions. The FMOC (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective deprotection during the synthesis process. This compound is characterized by its chirality, as it is derived from L-threonine, an essential amino acid. Its structure includes a threonine backbone, which contributes to its role in forming peptides with specific biological activities. The tert-butyl ester group also aids in the purification and handling of the compound. NALPHA-FMOC-L-THREONINE TERT-BUTYL ESTER is typically utilized in solid-phase peptide synthesis and other synthetic methodologies where protection of functional groups is necessary. Its stability under various conditions and compatibility with standard coupling reagents make it a valuable intermediate in the field of medicinal chemistry and biochemistry.
Formula:C23H27NO5
InChI:InChI=1/C23H27NO5/c1-14(25)20(21(26)29-23(2,3)4)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20,25H,13H2,1-4H3,(H,24,27)/t14-,20+/m1/s1
Synonyms:
  • Nalpha-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Threonine Tert-Butyl Ester
  • Fmoc-Thr-OtBu
  • tert-butyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threoninate
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