CAS 120796-97-6
:big endothelin 38 human
Description:
Big endothelin-1 (often referred to as big endothelin-38 in the context of human biology) is a precursor peptide involved in the regulation of vascular tone and blood pressure. It is part of the endothelin family, which includes several isoforms that are produced by endothelial cells. The substance is characterized by its relatively large molecular structure, which is cleaved to form active endothelin peptides, specifically endothelin-1, -2, and -3. These peptides are potent vasoconstrictors and play a crucial role in various physiological processes, including cardiovascular function and fluid balance. Big endothelin-1 is typically released in response to various stimuli, including hypoxia and inflammation, and its levels can be indicative of certain pathological conditions, such as heart failure and pulmonary hypertension. The CAS number 120796-97-6 specifically identifies this precursor peptide, which is important for research and clinical applications in understanding cardiovascular health and disease mechanisms.
Formula:C189H282N48O56S5
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.
Big Endothelin-1 (human)
CAS:Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-7.Formula:C189H282N48O56S5Purity:94.0%Color and Shape:White PowderMolecular weight:4282.94Big Endothelin-1 (Human, 1-38)
CAS:<p>This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.5mg vial. Big Endothelin-1 (Human, 1-38) is a peptide that is a member of the endothelin family and is part of the 39 amino acids of Big Endothelin-1 which is a precursor of Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.<br>Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.</p>Formula:C189H282N48O56S5Purity:Min. 95%Molecular weight:4,282.9 g/molBig Endothelin-1 (human)
CAS:<p>Please enquire for more information about Big Endothelin-1 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C189H282N48O56S5Purity:Min. 95%Molecular weight:4,282.88 g/molBig Endothelin-1 (Human, 1-38)
CAS:<p>This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial. Big Endothelin-1 (Human, 1-38) is part of the full lengthed 29 amino acid peptide Big Endothlin-1 which is a precursor peptide of the vasoconstrictorEndothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.<br>Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.</p>Formula:C189H282N48O56S5Purity:Min. 95%Molecular weight:4,282.9 g/mol
