CAS 1208319-26-9
:Oclacitinib
Description:
Oclacitinib is a selective Janus kinase (JAK) inhibitor primarily used in veterinary medicine, particularly for the treatment of allergic dermatitis in dogs. It works by modulating the immune response and reducing inflammation by inhibiting the activity of JAK enzymes, which play a crucial role in the signaling pathways of various cytokines and growth factors. The chemical structure of oclacitinib includes a pyrimidine ring and a phenyl group, contributing to its pharmacological properties. It is administered orally and has a favorable pharmacokinetic profile, allowing for effective absorption and distribution in the body. Oclacitinib is generally well-tolerated, but potential side effects may include gastrointestinal disturbances and changes in blood cell counts. Its use is regulated, and it is important for veterinarians to monitor patients for any adverse reactions during treatment. Overall, oclacitinib represents a significant advancement in the management of allergic conditions in dogs, providing relief from symptoms while minimizing the need for corticosteroids.
- PF-03394197 maleate
- Oclacitinib maleate
- VQIGDTLRBSNOBV-DYXOGNCHSA-N
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Found 9 products.
N-Methyl-1-(Trans-4-(Methyl(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Cyclohexyl)Methanesulfonamide
CAS:<p>N-Methyl-1-(Trans-4-(Methyl(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Cyclohexyl)Methanesulfonamide</p>Purity:98%Molecular weight:337.44g/molOclacitinib Maleate
CAS:Formula:C15H23N5O2S·C4H4O4Color and Shape:Off-White SolidMolecular weight:337.45 116.07Oclacitinib
CAS:<p>Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000</p>Formula:C15H23N5O2SPurity:98% - 98.45%Color and Shape:White To Off-White SolidMolecular weight:337.44Oclacitinib
CAS:<p>Applications Oclacitinib is a novel Janus kinase (JAK) inhibitor with activity against cytokines involved in allergy.<br>References Gonzales, A.J., et al.: J. Vet. Pharmacol. Ther., 37, 317 (2014)<br></p>Formula:C15H23N5O2SColor and Shape:NeatMolecular weight:337.44Oclacitinib
CAS:<p>Inhibitor of Janus kinase JAK1</p>Formula:C15H23N5O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:337.44 g/mol
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